ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-29.PDB
Scoring matrix: BEM1-D1_JO8-LCK-29_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 18.41
Foldx random average score for Saccharomyces cerevisiae: 13.380

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1326587
Proteins after disorder filtering: 4436
 Total fragments: 63194
Proteins after pattern filtering: 2099
 Total fragments: 11555
Proteins after MINT filtering: 9
 Total fragments: 76


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

18.41

2.76

0.00

Best peptides

RMRPGTKHFH

0.00

-0.83

-3.59

         
Interactors      
P38041

GRAPKPPSYP

9.00

-4.25

-7.01

PPQPGSKKGL

9.60

-2.88

-5.64

VQPPQSPSFN

9.73

-4.91

-7.67

P29366

PYIPGPVPYV

6.38

-4.47

-7.23

IMPYIPGPVP

11.14

-7.57

-10.33

YIPGPVPYVT

12.69

-5.03

-7.79

P21268

LNLSKPISPP

9.93

-5.59

-8.35

KPISPPPSLK

12.35

-5.43

-8.19

SKPISPPPSL

12.73

-5.48

-8.24

P11433

SNPSATPNME

8.91

-9.13

-11.89

P50090

ALPWSPESKN

11.94

-7.03

-9.79

VTPTLPPNQH

12.32

-8.96

-11.72

PTLPPNQHRG

12.79

-9.78

-12.54

P32618

EPSPKPSHKR

7.50

-6.56

-9.32

DVPIVPGNNT

9.65

-7.35

-10.11

KVPAKEPSPK

10.06

-5.30

-8.06

Q03497

SFPSKNPLKN

7.71

-8.60

-11.36

KPKVKPSKPE

8.14

-4.70

-7.46

VKPSKPEAKS

8.80

-6.61

-9.37

P39969

AQPPKSPLLN

6.20

-7.22

-9.98

RRAPKPPSYP

8.57

-5.58

-8.34

PPQPGSKKGL

9.60

-2.88

-5.64

P22224

MTPSTPTFPN

10.96

-7.68

-10.44

STPTFPNANG

12.52

-4.88

-7.64

SNGYQSPMTP

12.53

-4.12

-6.88

 


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