ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-2.PDB
Scoring matrix: BEM1-D1_JO8-LCK-2_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 19.33
Foldx random average score for Saccharomyces cerevisiae: 18.055

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1370736
Proteins after disorder filtering: 4413
 Total fragments: 81408
Proteins after pattern filtering: 2257
 Total fragments: 17734
Proteins after MINT filtering: 10
 Total fragments: 123


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

19.33

3.15

0.00

Best peptides

IRRRRFRDRR

0.00

5.77

2.62

         
Interactors      
P38041

GRAPKPPSYP

12.19

-2.06

-5.21

IFESPGRAPK

12.30

-5.39

-8.54

FKLVPPQPGS

12.45

0.94

-2.21

P29366

KRIMPYIPGP

9.54

-4.61

-7.76

IMPYIPGPVP

11.51

-3.40

-6.55

PYIPGPVPYV

14.58

-0.34

-3.49

P21268

LNLSKPISPP

10.14

-4.35

-7.50

SKPISPPPSL

13.68

-1.64

-4.79

KPISPPPSLK

15.56

-4.03

-7.18

P11433

TNSNPSATPN

16.75

-1.89

-5.04

P50090

IVTPTLPPNQ

13.56

-2.83

-5.98

ASTALPWSPE

14.45

-0.05

-3.20

TALPWSPESK

17.21

-1.04

-4.19

P32618

AKEPSPKPSH

11.22

0.13

-3.02

PVSYSPSNEP

12.70

-3.68

-6.83

VPAKEPSPKP

12.77

-5.23

-8.38

Q03497

HKQHKPKVKP

6.21

-3.50

-6.65

IPSRPAPKPP

10.26

-6.71

-9.86

HKPKVKPSKP

11.01

-6.92

-10.07

P39969

RRAPKPPSYP

8.46

-3.89

-7.04

VSPRRAPKPP

10.06

-6.58

-9.73

ARSSSPEENP

12.13

-2.58

-5.73

P22224

QSPMTPSTPT

13.84

-0.79

-3.94

IFPSTPGTID

14.35

-1.86

-5.01

PSTPTFPNAN

15.96

-2.63

-5.78

P35735

PHFNPQSSEK

15.02

-4.59

-7.74

LASPHFNPQS

16.10

-2.85

-6.00

ASPHFNPQSS

17.73

-0.84

-3.99

 


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