ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-19.PDB
Scoring matrix: BEM1-D1_JO8-LCK-19_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAGAAA
Foldx wt ligand score: 14.63
Foldx random average score for Saccharomyces cerevisiae: 14.214

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3207542
Proteins after random average filtering: 7179
 Total fragments: 1501286
Proteins after disorder filtering: 4533
 Total fragments: 74094
Proteins after pattern filtering: 2052
 Total fragments: 8072
Proteins after MINT filtering: 8
 Total fragments: 61


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAGAAA

14.63

-0.15

0.00

Best peptides

DMKKRGRSF

0.00

0.39

0.54

         
Interactors      
P38041

VQPPQSPSF

10.46

-1.00

-0.85

VPPQPGSKK

10.77

-4.33

-4.18

PQSPSFNNR

11.19

-6.19

-6.04

P29366

KRIMPYIPG

13.33

-3.34

-3.19

MPYIPGPVP

13.56

-4.80

-4.65

P50090

PTLPPNQHR

12.20

-5.13

-4.98

LPWSPESKN

13.56

-2.33

-2.18

IVTPTLPPN

14.12

-3.74

-3.59

P32618

VPIVPGNNT

11.24

-2.72

-2.57

KEPSPKPSH

12.34

-2.43

-2.28

SEPAPLPSH

12.42

-2.11

-1.96

Q03497

PPIPPTKSK

9.90

-4.39

-4.24

HKPKVKPSK

10.79

-2.03

-1.88

PKPPSSASA

10.90

-2.69

-2.54

P39969

LPPQPGSKK

10.70

-4.90

-4.75

APKPPSYPS

11.33

-2.49

-2.34

AQPPKSPLL

11.38

-4.15

-4.00

P22224

PMTPSTPTF

10.76

-2.60

-2.45

YQSPMTPST

12.99

-4.39

-4.24

FPSTPGTID

13.39

-1.77

-1.62

P35735

LASPHFNPQ

13.24

-0.39

-0.24

PHFNPQSSE

13.53

-2.05

-1.90

 


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