ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: BEM1-D1_JO8-LCK-1.PDB
Scoring matrix: BEM1-D1_JO8-LCK-1_mat
Uniprot code: P29366
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAAAAA
Foldx wt ligand score: 22.68
Foldx random average score for Saccharomyces cerevisiae: 20.227

Available information for P29366 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 1
Nš of interactions described: 42
 Interactions with other species: 2

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3200363
Proteins after random average filtering: 7179
 Total fragments: 1557420
Proteins after disorder filtering: 4460
 Total fragments: 80588
Proteins after pattern filtering: 2240
 Total fragments: 16031
Proteins after MINT filtering: 10
 Total fragments: 116


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAAAAA

22.68

-4.26

0.00

Best peptides

FRERKFRRRY

0.00

2.00

6.26

         
Interactors      
P38041

FKLVPPQPGS

14.33

-5.57

-1.31

GRAPKPPSYP

14.41

-10.68

-6.42

SPGRAPKPPS

16.02

-7.88

-3.62

P29366

KRIMPYIPGP

13.57

-7.54

-3.28

MPYIPGPVPY

16.94

-8.95

-4.69

IMPYIPGPVP

18.70

-8.08

-3.82

P21268

LNLSKPISPP

15.95

-9.13

-4.87

SKPISPPPSL

16.33

-7.34

-3.08

PLNLSKPISP

17.49

-8.70

-4.44

P11433

NSNPSATPNM

18.68

-4.89

-0.63

TNSNPSATPN

19.94

-3.68

0.58

YTNSNPSATP

20.16

-6.85

-2.59

P50090

ALPWSPESKN

17.33

-6.94

-2.68

VTPTLPPNQH

17.91

-6.19

-1.93

RIVTPTLPPN

17.98

-10.47

-6.21

P32618

KSEPAPLPSH

15.34

-6.20

-1.94

AKEPSPKPSH

15.70

-5.98

-1.72

RLSNDVPIVP

15.72

-11.88

-7.62

Q03497

FPSKNPLKNS

13.77

-9.12

-4.86

FIPSRPAPKP

14.06

-10.33

-6.07

HKQHKPKVKP

14.10

-9.46

-5.20

P39969

VSPRRAPKPP

11.76

-9.63

-5.37

RRAPKPPSYP

12.30

-11.48

-7.22

FKLLPPQPGS

14.56

-5.05

-0.79

P22224

QSPMTPSTPT

17.53

-5.49

-1.23

PSTPTFPNAN

18.48

-6.14

-1.88

SNGYQSPMTP

19.03

-6.16

-1.90

P35735

PLASPHFNPQ

16.86

-6.91

-2.65

PHFNPQSSEK

18.36

-7.33

-3.07

LASPHFNPQS

18.84

-7.51

-3.25

 


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