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Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: ABP1_1OV32-23.PDB
Scoring matrix: ABP1_1OV32-23_mat
Uniprot code: P15891
Genome source: Saccharomyces cerevisiae
Wild-type ligand: AAAAAAA
Foldx wt ligand score: 13.57
Foldx random average score for Saccharomyces cerevisiae: 12.328

Available information for P15891 in MINT (Nov 2008):
Nº of interacting proteins: 39
 Proteins belonging to other specie: 0
Nº of interactions described: 88
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3221900
Proteins after random average filtering: 7179
 Total fragments: 1821799
Proteins after disorder filtering: 4884
 Total fragments: 119110
Proteins after pattern filtering: 2290
 Total fragments: 15506
Proteins after MINT filtering: 35
 Total fragments: 603

Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

AAAAAAA

13.57

-1.27

0.00

Best peptides

RPRIPMH

0.00

-3.75

-2.48

         
Interactors      
P09119

TPTTSPV

9.50

-1.84

-0.57

VPLTPTT

10.61

-2.96

-1.69

LTPTTSP

11.45

-2.64

-1.37

P43603

TAPTSPS

9.34

-1.56

-0.29

FTAPTSP

11.20

-3.88

-2.61

P53145

PLLPPLP

7.54

-5.41

-4.14

PPLPGQP

9.39

-5.33

-4.06

PGQPPLI

9.82

-4.33

-3.06

Q08957

TPTRPLS

6.94

-2.38

-1.11

TEPTPGP

8.40

-2.15

-0.88

LPSTPTR

9.54

-3.77

-2.50

P16649

KPIPPFL

5.90

-6.34

-5.07

HSKPIPP

6.78

-4.66

-3.39

SPLGPEY

8.81

-2.44

-1.17

P48562

FPRGPMH

6.07

-2.99

-1.72

TAPKPPI

7.16

-2.13

-0.86

NPYRPHH

7.27

-1.74

-0.47

P40341

RNIPPPP

5.92

-6.75

-5.48

PPKPPLN

8.50

-4.62

-3.35

PPPPPPK

8.70

-5.09

-3.82

P17555

RPKKPST

6.19

-6.04

-4.77

PPRPKKP

7.17

-5.07

-3.80

PPPRPKK

7.86

-4.06

-2.79

P40494

RPPRPPP

5.77

-5.49

-4.22

RPPPKPL

6.27

-6.69

-5.42

KSRPPRP

6.28

-5.92

-4.65

P37298

PVLPQKP

8.88

-5.37

-4.10

LPQKPGG

10.30

-1.09

0.18

PQKPGGV

11.23

-3.66

-2.39

P04050

TCLPVPP

6.65

-4.49

-3.22

TYSPTSP

8.49

-3.32

-2.05

VPPPPVR

8.74

-5.12

-3.85

P40325

QPRPPPR

4.99

-5.87

-4.60

RPPPRPQ

6.43

-6.21

-4.94

QPPRPPR

6.71

-4.76

-3.49

P40095

RIPVLPP

6.54

-6.53

-5.26

PVLPPPR

7.19

-5.90

-4.63

PPRSPNR

8.31

-1.99

-0.72

Q12168

RGPPPLP

5.90

-7.04

-5.77

PPPVPNR

7.52

-5.14

-3.87

QHPVPKP

7.61

-5.32

-4.05

P08458

PKRKPPK

6.56

-3.51

-2.24

LPKRKPP

7.76

-3.71

-2.44

TPITNPS

7.98

-2.49

-1.22

Q06449

LPPPPQY

8.41

-4.57

-3.30

SNLPPPP

9.11

-4.79

-3.52

QPFPPPS

9.70

-4.02

-2.75

P32793

HGPTHPS

9.75

-2.44

-1.17

GHGPTHP

11.16

-4.25

-2.98

PTHPSNM

11.70

-3.69

-2.42

P32790

PPIKPPR

6.60

-3.25

-1.98

APLDPFK

7.65

-2.89

-1.62

TTVPAAP

7.96

-3.43

-2.16

Q06337

TPRPNPT

5.87

-3.29

-2.02

TQPRKPL

6.80

-2.95

-1.68

QPRKPLD

6.81

-1.75

-0.48

Q01389

RSKPLPP

6.47

-7.20

-5.93

KPLPPQL

7.09

-6.72

-5.45

TPSRPVP

7.27

-3.15

-1.88

P22082

RPRGRPK

5.86

-4.79

-3.52

PPKPQKP

8.61

-5.55

-4.28

KPQKPVP

8.64

-4.08

-2.81

P53974

KPKPPPK

6.34

-6.62

-5.35

HLKPKPP

6.55

-4.68

-3.41

TKPTPPP

7.39

-2.42

-1.15

Q06836

SRGPLLP

10.75

-4.12

-2.85

PLLPDDA

10.91

-3.48

-2.21

NKPPLSP

10.96

-3.64

-2.37

Q05580

LNLPQLP

7.86

-5.23

-3.96

PQLPPPK

8.05

-5.89

-4.62

LPPPKPK

8.42

-5.31

-4.04

P53933

RRRPPPP

4.16

-8.19

-6.92

RRPPPPP

6.27

-7.76

-6.49

RPPPPPI

6.72

-7.01

-5.74

Q04439

KPKEPMF

7.91

-2.79

-1.52

RPSPPTA

8.50

-5.19

-3.92

NARPSPP

8.65

-4.19

-2.92

Q08873

TKKPRPP

5.65

-4.88

-3.61

KPRPPVK

5.97

-6.19

-4.92

KKPRPPV

8.76

-3.33

-2.06

P38885

TAAPPSP

7.86

-3.85

-2.58

APPSPEN

11.54

-1.03

0.24

AAPPSPE

11.64

-2.97

-1.70

P50942

RPCPPIR

4.64

-8.13

-6.86

TPKPLPP

6.04

-5.40

-4.13

HPLKPCD

6.63

-3.54

-2.27

P48415

RPPVIPL

5.52

-6.72

-5.45

TKPRSGP

7.12

-2.79

-1.52

TSQPVGP

7.94

-3.55

-2.28

P40563

TPKVPER

2.09

-6.04

-4.77

TPNVPTR

5.37

-4.47

-3.20

PPPVPKK

7.35

-4.69

-3.42

P38822

PEVPPPR

8.69

-5.41

-4.14

APEVPPP

9.33

-3.78

-2.51

TPTTTPG

9.91

-1.96

-0.69

Q12134

HQPVPSP

6.97

-4.75

-3.48

QPVPSPM

9.52

-4.03

-2.76

PVPSPMN

11.99

-0.94

0.33

P39743

TIPEDNP

10.29

-1.29

-0.02

NPLTSPV

10.54

-2.84

-1.57

P47976

RPSPWLP

6.48

-6.73

-5.46

TLPINNP

7.08

-3.45

-2.18

YSPRPSP

8.61

-3.43

-2.16

 


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