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Matrix information:
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ADAN-name: 3GBQ2.PDB
Scoring matrix: 3GBQ2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: VPPPVPPRRR
Foldx wt ligand score: 0.97
Foldx random average score for Mus musculus: 9.379 Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
Proteins belonging to other specie: 6
Nš of interactions described: 55
Interactions with other species: 12
Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
Total fragments: 20375566
Proteins after random average filtering: 44441
Total fragments: 10311315
Proteins after disorder filtering: 32184
Total fragments: 1056289
Proteins after pattern filtering: 23137
Total fragments: 315612
Proteins after MINT filtering: 25
Total fragments: 740
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VPPPVPPRRR |
0.97
|
-13.71 |
0.00 |
| Best peptides |
IMVEMPRRGH |
0.00
|
-8.73 |
4.98 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q62245 |
VPPPVPPRRR |
0.97
|
-13.32 |
0.39 |
|
SPPAIPPRQP |
1.42
|
-13.11 |
0.60 |
|
PPPVPPRRRP |
1.51
|
-13.11 |
0.60 |
| Q02384 |
DPPAIPPRQP |
1.42
|
-12.81 |
0.90 |
|
PAPPVPPRQN |
1.77
|
-13.31 |
0.40 |
|
IPPPLPPRKK |
1.85
|
-12.85 |
0.86 |
| P39054 |
IPPGVPSRRA |
0.95
|
-12.09 |
1.62 |
|
AAPSRPTIIR |
2.34
|
-9.47 |
4.24 |
|
IPPGIPPGVP |
2.81
|
-8.30 |
5.41 |
| P35991 |
KKPLPPEPTA |
5.71
|
-8.27 |
5.44 |
|
KKPLPPTPEE |
6.14
|
-7.36 |
6.35 |
|
PLPPTPEEDQ |
7.50
|
-6.53 |
7.18 |
| Q9Z1S8 |
PRPPKPSQAE |
3.87
|
-9.35 |
4.36 |
|
PPPRPPKPSQ |
4.50
|
-8.78 |
4.93 |
|
EENYVPMQNP |
5.00
|
-6.33 |
7.38 |
| Q62077 |
DCWDGPDGMP |
5.31
|
-4.61 |
9.10 |
|
DGPDGMPVIY |
8.46
|
-4.28 |
9.43 |
| P70424 |
PPPIRPAGAT |
3.12
|
-7.62 |
6.09 |
|
EYVNQPEVRP |
3.86
|
-8.67 |
5.04 |
|
CLPCHPECQP |
3.92
|
-8.76 |
4.95 |
| Q8R550 |
RPGALPPRRP |
3.09
|
-10.19 |
3.52 |
|
SVPAIPPKKP |
3.38
|
-8.67 |
5.04 |
|
PKKPRPPKTN |
3.59
|
-9.06 |
4.65 |
| Q923U0 |
RLPPLPSSHP |
4.55
|
-9.09 |
4.62 |
|
LSPIVPVPTP |
4.56
|
-7.58 |
6.13 |
|
ISPNRPTSVP |
4.77
|
-6.73 |
6.98 |
| O35716 |
AAPVRPRPCP |
3.32
|
-7.90 |
5.81 |
|
PCPAVPAPAP |
3.88
|
-7.59 |
6.12 |
|
PAVPAPAPGD |
4.45
|
-6.44 |
7.27 |
| Q80U87 |
VHMYPPEMAP |
3.72
|
-8.58 |
5.13 |
|
LEEPVPSKLP |
4.19
|
-7.51 |
6.20 |
|
APPSTPPTHK |
4.29
|
-7.95 |
5.76 |
| Q61234 |
SPPASPLQRQ |
3.69
|
-8.95 |
4.76 |
|
GPEPEPAQLN |
4.64
|
-7.52 |
6.19 |
|
PADGEPGPEP |
6.16
|
-5.62 |
8.09 |
| Q9JLQ0 |
AAPQVPPKKP |
1.58
|
-9.67 |
4.04 |
|
KKPPPPAKGP |
2.76
|
-10.08 |
3.63 |
|
EPVSKPKLDP |
3.48
|
-7.90 |
5.81 |
| Q60749 |
PPPPVPRGRG |
2.26
|
-10.27 |
3.44 |
|
PLPHRPRGGG |
3.08
|
-9.10 |
4.61 |
|
APPPPPVPRG |
3.83
|
-9.99 |
3.72 |
| Q99JZ7 |
RPPKVPPREP |
1.85
|
-12.12 |
1.59 |
|
TPPLTPIKSC |
2.55
|
-9.07 |
4.64 |
|
DKPEVPPRVP |
2.64
|
-12.77 |
0.94 |
| Q9QUN3 |
GPPSVPRRDY |
1.80
|
-12.16 |
1.55 |
|
SPVFPPTQKP |
2.81
|
-8.66 |
5.05 |
|
PPTQKPVHQK |
3.23
|
-7.89 |
5.82 |
| P27870 |
IPPPPGAFGP |
5.17
|
-7.32 |
6.39 |
|
YGIPPPPGAF |
5.50
|
-6.06 |
7.65 |
|
YYGIPPPPGA |
5.99
|
-5.59 |
8.12 |
| P04925 |
NQWNKPSKPK |
8.11
|
-9.01 |
4.70 |
| Q9WU78 |
PPPVLPANRV |
2.76
|
-10.38 |
3.33 |
|
NMPYPPVYHQ |
2.84
|
-10.04 |
3.67 |
|
APRTMPPAKP |
3.02
|
-6.95 |
6.76 |
| Q60992 |
PPTGRPPSRE |
4.70
|
-9.26 |
4.45 |
|
ADVDAPGAGP |
5.44
|
-4.93 |
8.78 |
|
HGNPAPPGKP |
5.47
|
-5.16 |
8.55 |
| P98083 |
PPPPCPGREL |
2.60
|
-10.72 |
2.99 |
|
GPKGEPGKAA |
3.62
|
-6.91 |
6.80 |
|
LRVPPPPQSM |
4.03
|
-8.26 |
5.45 |
| Q9EQ32 |
RPPRVPPRAA |
1.71
|
-13.08 |
0.63 |
|
VPVPRPEASA |
3.34
|
-8.18 |
5.53 |
|
GPPPPPDNEP |
3.65
|
-9.96 |
3.75 |
| Q61824 |
PAPIRPAPKH |
3.30
|
-8.53 |
5.18 |
|
TAPHCPANVY |
3.65
|
-8.07 |
5.64 |
|
APIRPAPKHQ |
4.12
|
-6.72 |
6.99 |
| Q91ZZ2 |
SPPALPPKKR |
2.02
|
-10.32 |
3.39 |
|
PPPALPPKQR |
2.25
|
-9.78 |
3.93 |
|
PPALPPKKRQ |
2.87
|
-8.95 |
4.76 |
| Q9QYY0 |
SSPKTPPRRP |
2.87
|
-10.01 |
3.70 |
|
PPKPHPTHDR |
3.54
|
-7.96 |
5.75 |
|
NPNSPPRQHS |
3.58
|
-9.01 |
4.70 |
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