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Matrix information:
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ADAN-name: 2VKN2.PDB
Scoring matrix: 2VKN2_mat
Uniprot code: P40073
Genome source: Saccharomyces cerevisiae
Wild-type ligand: KPLPPLPLA
Foldx wt ligand score: 2.79
Foldx random average score for Saccharomyces cerevisiae: 9.277 Available information for P40073 in MINT (Nov 2008):
Nš of interacting proteins: 56
Proteins belonging to other specie: 0
Nš of interactions described: 68
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
Total fragments: 3207542
Proteins after random average filtering: 7179
Total fragments: 1520348
Proteins after disorder filtering: 4308
Total fragments: 51986
Proteins after pattern filtering: 2170
Total fragments: 12159
Proteins after MINT filtering: 35
Total fragments: 407
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KPLPPLPLA |
2.79
|
-13.42 |
0.00 |
| Best peptides |
RRLRFLMRE |
0.00
|
-14.05 |
-0.63 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P11710 |
KPLPLTPNS |
4.74
|
-11.73 |
1.69 |
|
PLTPNSKYN |
8.80
|
-7.88 |
5.54 |
|
LPLTPNSKY |
9.20
|
-7.56 |
5.86 |
| Q06604 |
PLLPTRPNK |
4.73
|
-11.14 |
2.28 |
|
PPLPTRRDH |
5.10
|
-11.05 |
2.37 |
|
RVKPAPPVS |
6.00
|
-9.76 |
3.66 |
| P24814 |
RLHPPDIHP |
6.46
|
-10.35 |
3.07 |
|
PNLGPQLWL |
6.47
|
-8.82 |
4.60 |
|
NSTRPQMPS |
7.08
|
-9.66 |
3.76 |
| P40073 |
DGYPQQQPS |
8.65
|
-7.57 |
5.85 |
|
GYPQQQPSH |
8.84
|
-7.33 |
6.09 |
|
FDGYPQQQP |
9.11
|
-6.69 |
6.73 |
| P24583 |
APLPPQPRK |
4.72
|
-12.42 |
1.00 |
|
RANAPLPPQ |
6.08
|
-10.55 |
2.87 |
|
PPQPRKHDK |
7.55
|
-9.64 |
3.78 |
| Q06412 |
RRPPPPPPL |
5.57
|
-11.75 |
1.67 |
|
PKLPPLNTR |
5.66
|
-10.99 |
2.43 |
|
RPPPPPPLL |
5.70
|
-11.18 |
2.24 |
| P40036 |
KSLPTTPGI |
4.48
|
-11.45 |
1.97 |
|
IELPPLSPK |
5.59
|
-12.36 |
1.06 |
|
PTTPGIRSG |
7.07
|
-9.13 |
4.29 |
| P18494 |
RSVVPILPK |
5.74
|
-11.16 |
2.26 |
|
SVVPILPKP |
6.49
|
-10.24 |
3.18 |
|
VPILPKPSP |
7.99
|
-8.62 |
4.80 |
| P40055 |
SDIPDVKPD |
8.01
|
-9.33 |
4.09 |
|
PDVKPDVKG |
8.05
|
-8.79 |
4.63 |
| P09620 |
PSNIPQMHA |
7.68
|
-8.63 |
4.79 |
|
SNPISKPSI |
8.04
|
-7.78 |
5.64 |
|
PDPSNIPQM |
8.35
|
-8.16 |
5.26 |
| P13186 |
EPLPEREPP |
6.74
|
-9.89 |
3.53 |
|
IPLTPLATN |
7.08
|
-8.45 |
4.97 |
|
LPEREPPTY |
7.17
|
-11.77 |
1.65 |
| P04051 |
RSLPHFPKN |
4.14
|
-11.68 |
1.74 |
|
SVNPAMLPG |
7.50
|
-9.67 |
3.75 |
|
VNPAMLPGS |
8.07
|
-8.45 |
4.97 |
| P32334 |
FSSPSSPTT |
9.08
|
-7.35 |
6.07 |
| P39083 |
HLLQSPATP |
7.60
|
-8.32 |
5.10 |
|
PATPSNVSM |
8.24
|
-8.63 |
4.79 |
|
LQSPATPSN |
8.92
|
-7.44 |
5.98 |
| P38753 |
PVMPPQRQS |
6.06
|
-10.46 |
2.96 |
|
SNLPIQHPT |
6.53
|
-9.57 |
3.85 |
|
NNTPVMPPQ |
6.89
|
-9.55 |
3.87 |
| Q06524 |
KYNPTVPNE |
6.12
|
-10.13 |
3.29 |
|
PTVPNELLP |
6.44
|
-10.00 |
3.42 |
| P40020 |
RVLPPLPFP |
2.24
|
-14.41 |
-0.99 |
|
MSLPVTPVK |
4.74
|
-11.35 |
2.07 |
|
ISLPPYLSP |
5.31
|
-10.68 |
2.74 |
| Q00246 |
KNLPRLPTP |
2.78
|
-12.62 |
0.80 |
|
SNLPESPGT |
6.66
|
-10.07 |
3.35 |
|
PESPGTLDE |
8.22
|
-7.33 |
6.09 |
| P32448 |
PQLPSKDKS |
6.31
|
-8.94 |
4.48 |
|
TDSPQLPSK |
7.22
|
-8.55 |
4.87 |
|
PRVPTDSPQ |
8.24
|
-9.04 |
4.38 |
| Q08229 |
RPLPSTPNE |
3.27
|
-12.67 |
0.75 |
|
LPTPVQPGG |
6.63
|
-10.08 |
3.34 |
|
PSTPNEDSR |
8.21
|
-8.28 |
5.14 |
| Q04439 |
KPAPPPPGM |
6.17
|
-10.76 |
2.66 |
|
SSKPKEPMF |
6.60
|
-8.76 |
4.66 |
|
PPPPGMQNK |
6.81
|
-9.05 |
4.37 |
| P35197 |
RPDHLPPSQ |
6.87
|
-8.73 |
4.69 |
|
GSTPAKPPQ |
7.19
|
-9.18 |
4.24 |
|
PAKPPQERS |
8.44
|
-8.25 |
5.17 |
| Q12446 |
RPLPQLPNR |
2.31
|
-13.65 |
-0.23 |
|
HSLPPLPNQ |
2.94
|
-13.99 |
-0.57 |
|
PPLPNQFAP |
5.03
|
-10.41 |
3.01 |
| P08018 |
PRLPSDKFS |
4.62
|
-11.58 |
1.84 |
|
RAPRRPLST |
5.72
|
-10.12 |
3.30 |
|
GPPPRLPSD |
6.78
|
-10.18 |
3.24 |
| P53552 |
RALRPTGPD |
6.06
|
-10.19 |
3.23 |
|
QALPQGPKG |
6.40
|
-8.98 |
4.44 |
|
RPTGPDRGD |
7.45
|
-10.03 |
3.39 |
| P39969 |
KLLPPQPGS |
3.50
|
-13.07 |
0.35 |
|
KALSPIPSP |
5.28
|
-10.87 |
2.55 |
|
RRAPKPPSY |
5.71
|
-10.79 |
2.63 |
| P46674 |
STSPPLPSH |
7.73
|
-9.12 |
4.30 |
|
PVTPVLDGA |
7.79
|
-8.37 |
5.05 |
|
PINPVTPVL |
8.42
|
-8.19 |
5.23 |
| P14906 |
YGHPDGPQS |
8.77
|
-6.85 |
6.57 |
|
KYGHPDGPQ |
8.83
|
-6.51 |
6.91 |
| Q03790 |
PSAPQPLFM |
7.41
|
-8.54 |
4.88 |
|
TATPSPFRP |
8.05
|
-8.61 |
4.81 |
|
NGFPSAPQP |
8.62
|
-7.52 |
5.90 |
| P40568 |
APTPAMIPY |
7.81
|
-10.10 |
3.32 |
|
PAMIPYPGS |
7.93
|
-8.20 |
5.22 |
|
IPYPGSPMH |
8.16
|
-8.47 |
4.95 |
| Q12443 |
PDPITVPAP |
8.84
|
-7.21 |
6.21 |
|
IPDPITVPA |
9.21
|
-7.62 |
5.80 |
| P41809 |
PSVPVAVSS |
8.75
|
-7.70 |
5.72 |
|
STYPTTPYP |
8.83
|
-7.39 |
6.03 |
|
TSSPSVPVA |
9.10
|
-6.63 |
6.79 |
| Q05080 |
RQKPDKPRP |
5.18
|
-10.93 |
2.49 |
|
KPDKPRPIV |
6.47
|
-9.95 |
3.47 |
|
LRQKPDKPR |
6.78
|
-10.13 |
3.29 |
| P53297 |
MYMPFQPQP |
4.68
|
-11.20 |
2.22 |
|
PSMPQMMPV |
5.20
|
-10.80 |
2.62 |
|
SSLPPKPIS |
5.27
|
-11.34 |
2.08 |
| P22147 |
FPPPPPMTN |
6.81
|
-10.41 |
3.01 |
|
NGLHPLHPH |
6.84
|
-9.05 |
4.37 |
|
VGLPYNIPP |
6.95
|
-11.21 |
2.21 |
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