ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2R4H2.PDB
Scoring matrix: 2R4H2_mat
Uniprot code: Q96QZ7
Genome source: Homo sapiens
Wild-type ligand: GETSV
Foldx wt ligand score: 3.56
Foldx random average score for Homo sapiens: 10.394

Available information for Q96QZ7 in MINT (Nov 2008):
Nš of interacting proteins: 16
 Proteins belonging to other specie: 10
Nš of interactions described: 16
 Interactions with other species: 10

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22344792
Proteins after random average filtering: 48054
 Total fragments: 11777786
Proteins after disorder filtering: 37450
 Total fragments: 1338132
Proteins after pattern filtering: 29005
 Total fragments: 155556
Proteins after MINT filtering: 4
 Total fragments: 47


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

GETSV

3.56

-8.25

0.00

Best peptides

FMDYM

0.00

-8.38

-0.13

         
Interactors      
Q13625

PAAAV

5.68

-6.45

1.80

GSASV

5.94

-6.83

1.42

GQVSL

5.96

-5.75

2.50

P05549

PYSHV

5.10

-8.58

-0.33

PYTSA

6.71

-4.84

3.41

GTARL

6.76

-3.76

4.49

Q14118

PPTEV

4.30

-9.85

-1.60

TETMA

4.41

-6.33

1.92

PPFTV

4.73

-8.98

-0.73

P20936

VETGV

3.62

-9.89

-1.64

GDYSL

3.86

-7.96

0.29

GGAAL

6.12

-4.71

3.54

 


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