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Matrix information:
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ADAN-name: 2PZD2.PDB
Scoring matrix: 2PZD2_mat
Uniprot code: O43464
Genome source: Homo sapiens
Wild-type ligand: GWTMFWV
Foldx wt ligand score: 1.88
Foldx random average score for Homo sapiens: 15.856 Available information for O43464 in MINT (Nov 2008):
Nš of interacting proteins: 5
Proteins belonging to other specie: 0
Nš of interactions described: 7
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22248677
Proteins after random average filtering: 48051
Total fragments: 14027482
Proteins after disorder filtering: 36906
Total fragments: 1227300
Proteins after pattern filtering: 28115
Total fragments: 150292
Proteins after MINT filtering: 5
Total fragments: 13
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
GWTMFWV |
1.88
|
-19.84 |
0.00 |
| Best peptides |
WWWMMWI |
0.00
|
-17.28 |
2.56 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q93009 |
GHYVVYL |
10.38
|
-15.20 |
4.64 |
|
HGGHYVV |
12.60
|
-12.28 |
7.56 |
|
PRPWLGL |
13.80
|
-12.03 |
7.81 |
| Q99982 |
FKKHFPV |
12.06
|
-14.00 |
5.84 |
|
EILPSSL |
14.70
|
-11.98 |
7.86 |
| P98170 |
FPNSTNL |
15.29
|
-8.62 |
11.22 |
| Q13489 |
GTVRTFL |
11.65
|
-12.99 |
6.85 |
|
PTFPSSV |
13.88
|
-11.54 |
8.30 |
|
NSTHSLL |
13.94
|
-12.23 |
7.61 |
| Q13490 |
GTVRTFL |
11.65
|
-12.99 |
6.85 |
|
PMRNSFA |
12.64
|
-13.49 |
6.35 |
|
SGSYSSL |
14.70
|
-9.18 |
10.66 |
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