ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2OS62.PDB
Scoring matrix: 2OS62_mat
Uniprot code: Q9NZN5
Genome source: Homo sapiens
Wild-type ligand: VENKVTDL
Foldx wt ligand score: 7.06
Foldx random average score for Homo sapiens: 9.045

Available information for Q9NZN5 in MINT (Nov 2008):
Nš of interacting proteins: 3
 Proteins belonging to other specie: 2
Nš of interactions described: 11
 Interactions with other species: 4

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22200620
Proteins after random average filtering: 48040
 Total fragments: 10805698
Proteins after disorder filtering: 35018
 Total fragments: 654492
Proteins after pattern filtering: 23422
 Total fragments: 84612
Proteins after MINT filtering: 1
 Total fragments: 5


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

VENKVTDL

7.06

-3.85

0.00

Best peptides

HMHMMMEM

0.00

-7.24

-3.39

         
Interactors      
P08069

KNERALPL

4.62

-5.31

-1.46

GSQSMYCI

5.81

-4.00

-0.15

ASSSSLPL

6.13

-4.36

-0.51

 


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