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Matrix information:
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ADAN-name: 2OQS2.PDB
Scoring matrix: 2OQS2_mat
Uniprot code: Q12959
Genome source: Homo sapiens
Wild-type ligand: RRETQV
Foldx wt ligand score: 4.95
Foldx random average score for Homo sapiens: 10.302 Available information for Q12959 in MINT (Nov 2008):
Nš of interacting proteins: 23
Proteins belonging to other specie: 16
Nš of interactions described: 43
Interactions with other species: 22
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22296734
Proteins after random average filtering: 48057
Total fragments: 16899681
Proteins after disorder filtering: 38050
Total fragments: 1764917
Proteins after pattern filtering: 28242
Total fragments: 142587
Proteins after MINT filtering: 4
Total fragments: 11
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RRETQV |
4.95
|
-1.45 |
0.00 |
| Best peptides |
PWMDDV |
0.00
|
2.90 |
4.35 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q9UM54 |
PDSLTI |
5.59
|
-1.64 |
-0.19 |
|
GNIVDI |
6.04
|
-2.49 |
-1.04 |
| P22001 |
QDSFEA |
6.49
|
-0.52 |
0.93 |
|
TGNSTA |
7.25
|
0.40 |
1.85 |
|
GSRAGA |
7.91
|
2.11 |
3.56 |
| Q99759 |
SRHLSV |
3.83
|
-1.99 |
-0.54 |
| P78536 |
LQPAPV |
4.92
|
-1.31 |
0.14 |
|
PGIMYL |
6.15
|
-1.29 |
0.16 |
|
PNSSTA |
7.92
|
1.02 |
2.47 |
|
