ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2OPG2.PDB
Scoring matrix: 2OPG2_mat
Uniprot code: O75970
Genome source: Homo sapiens
Wild-type ligand: YKSTRL
Foldx wt ligand score: 5.71
Foldx random average score for Homo sapiens: 9.202

Available information for O75970 in MINT (Nov 2008):
Nš of interacting proteins: 6
 Proteins belonging to other specie: 1
Nš of interactions described: 17
 Interactions with other species: 5

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22296734
Proteins after random average filtering: 48050
 Total fragments: 11833187
Proteins after disorder filtering: 36787
 Total fragments: 814601
Proteins after pattern filtering: 29283
 Total fragments: 165246
Proteins after MINT filtering: 1
 Total fragments: 4


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

YKSTRL

5.71

-10.63

0.00

Best peptides

WWLMFF

0.00

-9.95

0.68

         
Interactors      
Q9HB19

LPSSRI

6.59

-8.07

2.56

QPWTPV

6.64

-9.32

1.31

GPNSIL

7.02

-8.40

2.23

 


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