Matrix information:
(Help) ADAN-name: 2OI32.PDB Scoring matrix: 2OI32_mat Uniprot code: P08631 Genome source: Homo sapiens Wild-type ligand: HSKYPLPPLPSL Foldx wt ligand score: 7.14 Foldx random average score for Homo sapiens: 15.972 Available information for P08631 in MINT (Nov 2008): Nš of interacting proteins: 16 Proteins belonging to other specie: 7 Nš of interactions described: 37 Interactions with other species: 17
Genome scanning information:
Subcellular location: False Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0 Proteins considered as fragments or having non-standard amino acids: 22829 Total scanned proteins: 48061 Total fragments: 22008420 Proteins after random average filtering: 48035 Total fragments: 11822935 Proteins after disorder filtering: 34071 Total fragments: 698049 Proteins after pattern filtering: 24855 Total fragments: 276312 Proteins after MINT filtering: 7 Total fragments: 194
Prediction of know targets:
Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
Reference wt |
HSKYPLPPLPSL |
7.14
|
-14.55 |
0.00 |
Best peptides |
PFMMRLPWLRKN |
0.00
|
-18.12 |
-3.57 |
|
|
|
|
|
Interactors |
|
|
|
|
Q92556 |
QIPDAPPPIPKE |
11.96
|
-12.41 |
2.14 |
|
DAPPPIPKEPSN |
13.56
|
-11.07 |
3.48 |
|
IPDAPPPIPKEP |
15.76
|
-11.37 |
3.18 |
Q53H12 |
GPTERPPNEPEE |
11.90
|
-10.34 |
4.21 |
|
ISYTGPTERPPN |
14.81
|
-6.98 |
7.57 |
|
TGPTERPPNEPE |
15.35
|
-8.40 |
6.15 |
Q13177 |
EDKPPAPPVRMS |
11.97
|
-12.26 |
2.29 |
|
PEKDGFPSGTPA |
13.65
|
-10.00 |
4.55 |
|
NHSLKPLPSVPE |
13.86
|
-8.35 |
6.20 |
O43516 |
PQRNRMPPPRPD |
7.17
|
-15.20 |
-0.65 |
|
PRSGPRPPLPPD |
9.88
|
-14.63 |
-0.08 |
|
PPQNNKPPVPST |
10.48
|
-13.43 |
1.12 |
P42768 |
ERRGGLPPLPLH |
8.37
|
-14.88 |
-0.33 |
|
RRQLPPPPTPAN |
9.46
|
-13.44 |
1.11 |
|
GNQLPRPPIVGG |
9.72
|
-12.34 |
2.21 |
P21860 |
PGIAPGPEPHGL |
9.94
|
-12.56 |
1.99 |
|
PIMPTAGTTPDE |
12.56
|
-9.81 |
4.74 |
|
CPLHPVPIMPTA |
12.65
|
-10.20 |
4.35 |
Q13444 |
PPRKPLPADPQG |
8.09
|
-14.62 |
-0.07 |
|
PSERPGPPQRAL |
11.18
|
-11.88 |
2.67 |
|
RAAQSGPSERPG |
11.92
|
-11.56 |
2.99 |
|