ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2O9V2.PDB
Scoring matrix: 2O9V2_mat
Uniprot code: Q9BX66
Genome source: Homo sapiens
Wild-type ligand: VPPPVPPPPS
Foldx wt ligand score: 3.35
Foldx random average score for Homo sapiens: 8.332

Available information for Q9BX66 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22104514
Proteins after random average filtering: 48042
 Total fragments: 11071717
Proteins after disorder filtering: 34806
 Total fragments: 1020237
Proteins after pattern filtering: 25595
 Total fragments: 405934
Proteins after MINT filtering: 2
 Total fragments: 53


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

VPPPVPPPPS

3.35

-11.51

0.00

Best peptides

DPPRIPRRIH

0.00

-13.83

-2.32

         
Interactors      
Q13444

PPLVVPSRPA

3.08

-12.92

-1.41

PPPPRKPLPA

3.22

-15.22

-3.71

QGPAKPPPPR

3.52

-11.39

0.12

Q13177

KPPAPPVRMS

3.74

-12.20

-0.69

DKPPAPPVRM

4.91

-10.21

1.30

PAPPVRMSST

6.18

-8.77

2.74

 


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