ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2JOA2.PDB
Scoring matrix: 2JOA2_mat
Uniprot code: Q92743
Genome source: Homo sapiens
Wild-type ligand: DSRIWWV
Foldx wt ligand score: 4.73
Foldx random average score for Homo sapiens: 7.514

Available information for Q92743 in MINT (Nov 2008):
Nš of interacting proteins: 1
 Proteins belonging to other specie: 0
Nš of interactions described: 1
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22248677
Proteins after random average filtering: 48054
 Total fragments: 14370899
Proteins after disorder filtering: 36828
 Total fragments: 1135404
Proteins after pattern filtering: 26877
 Total fragments: 123849
Proteins after MINT filtering: 1
 Total fragments: 1


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

DSRIWWV

4.73

-2.86

0.00

Best peptides

PGGMLPV

0.00

2.35

5.21

         
Interactors      
Q5TF85

SWGGSGA

6.94

-1.41

1.45

 


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