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Matrix information:
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ADAN-name: 2J7I2.PDB
Scoring matrix: 2J7I2_mat
Uniprot code: Q9Y5K6
Genome source: Homo sapiens
Wild-type ligand: GPPLPRPRV
Foldx wt ligand score: 4.7
Foldx random average score for Homo sapiens: 9.528 Available information for Q9Y5K6 in MINT (Nov 2008):
Nš of interacting proteins: 12
Proteins belonging to other specie: 2
Nš of interactions described: 24
Interactions with other species: 4
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22152566
Proteins after random average filtering: 48048
Total fragments: 11240282
Proteins after disorder filtering: 36092
Total fragments: 1372446
Proteins after pattern filtering: 25822
Total fragments: 438921
Proteins after MINT filtering: 9
Total fragments: 287
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
GPPLPRPRV |
4.70
|
-10.14 |
0.00 |
| Best peptides |
ADPPVIRRK |
0.00
|
-11.89 |
-1.75 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P27986 |
PKPRPPRPL |
4.61
|
-8.07 |
2.07 |
|
ISPPTPKPR |
5.08
|
-9.42 |
0.72 |
|
RPPRPLPVA |
5.21
|
-8.18 |
1.96 |
| P22681 |
SLPPVPPRL |
3.18
|
-12.61 |
-2.47 |
|
WLPRPIPKV |
3.79
|
-8.43 |
1.71 |
|
RPPKPFPRR |
3.81
|
-11.51 |
-1.37 |
| Q8WUM4 |
PYPPVYHQS |
4.06
|
-9.83 |
0.31 |
|
NMPYPPVYH |
4.09
|
-5.84 |
4.30 |
|
PFPQPPQQS |
4.36
|
-6.83 |
3.31 |
| P12931 |
QTPSKPASA |
7.57
|
-5.88 |
4.26 |
|
ASQTPSKPA |
8.19
|
-2.53 |
7.61 |
|
PSKPASADG |
8.22
|
-3.52 |
6.62 |
| P07947 |
VVPSSYPAG |
7.96
|
-3.79 |
6.35 |
|
VPSSYPAGL |
8.26
|
-4.97 |
5.17 |
|
PENTPEPVS |
8.80
|
-4.19 |
5.95 |
| Q99816 |
YMPGMPGGI |
4.59
|
-8.30 |
1.84 |
|
GCPYPPGGP |
6.41
|
-6.89 |
3.25 |
|
YPPGGPYPA |
6.69
|
-5.15 |
4.99 |
| P06729 |
HRPPPPGHR |
4.08
|
-8.50 |
1.64 |
|
HPPPPPGHR |
4.38
|
-9.67 |
0.47 |
|
QHPPPPPGH |
4.62
|
-8.39 |
1.75 |
| Q9H9H4 |
PPPPVPAGR |
3.32
|
-10.20 |
-0.06 |
|
GPPAVAPRR |
3.84
|
-13.33 |
-3.19 |
|
PYPPPLPQR |
3.89
|
-9.55 |
0.59 |
| P06241 |
TDPTPQHYP |
5.46
|
-8.11 |
2.03 |
|
TPQHYPSFG |
8.34
|
-3.16 |
6.98 |
|
PTPQHYPSF |
8.84
|
-5.52 |
4.62 |
|
