ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2I0L2.PDB
Scoring matrix: 2I0L2_mat
Uniprot code: Q62696
Genome source: Rattus norvegicus
Wild-type ligand: RRETQV
Foldx wt ligand score: 4.78
Foldx random average score for Rattus norvegicus: 8.326

Available information for Q62696 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 6
Nš of interactions described: 22
 Interactions with other species: 12

Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
 Total fragments: 5592797
Proteins after random average filtering: 11954
 Total fragments: 3863974
Proteins after disorder filtering: 9367
 Total fragments: 270632
Proteins after pattern filtering: 7247
 Total fragments: 36550
Proteins after MINT filtering: 3
 Total fragments: 14


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

RRETQV

4.78

-8.90

0.00

Best peptides

WMMMDL

0.00

-10.51

-1.61

         
Interactors      
Q9WVI4

CPLSKL

4.38

-9.43

-0.53

PPGSRA

7.59

-5.01

3.89

Q63226

TLGLNL

3.92

-8.88

0.02

NDDYTL

4.55

-7.40

1.50

NPVTGL

4.59

-8.68

0.22

Q00959

SCLSNL

3.98

-10.54

-1.64

RSKSLL

4.61

-8.51

0.39

EPSFHL

4.63

-7.69

1.21

 


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