ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 2I0I2.PDB
Scoring matrix: 2I0I2_mat
Uniprot code: Q62696
Genome source: Rattus norvegicus
Wild-type ligand: RRETQV
Foldx wt ligand score: 5.85
Foldx random average score for Rattus norvegicus: 8.257

Available information for Q62696 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 6
Nš of interactions described: 22
 Interactions with other species: 12

Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
 Total fragments: 5592797
Proteins after random average filtering: 11954
 Total fragments: 3533217
Proteins after disorder filtering: 9293
 Total fragments: 246201
Proteins after pattern filtering: 7005
 Total fragments: 32341
Proteins after MINT filtering: 3
 Total fragments: 12


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

RRETQV

5.85

-8.31

0.00

Best peptides

AKIEHV

0.00

-7.00

1.31

         
Interactors      
Q9WVI4

CPLSKL

8.11

-5.69

2.62

Q63226

TLGLNL

5.22

-6.86

1.45

NDDYTL

6.27

-6.52

1.79

KTMSSI

6.61

-5.55

2.76

Q00959

EPSFHL

5.75

-6.58

1.73

RSKSLL

6.67

-6.45

1.86

KGDSTL

6.96

-4.31

4.00

 


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