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Matrix information:
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ADAN-name: 2GBQ2.PDB
Scoring matrix: 2GBQ2_mat
Uniprot code: Q60631
Genome source: Mus musculus
Wild-type ligand: VPPPVPPRRR
Foldx wt ligand score: 2.01
Foldx random average score for Mus musculus: 10.600 Available information for Q60631 in MINT (Nov 2008):
Nš of interacting proteins: 32
Proteins belonging to other specie: 6
Nš of interactions described: 55
Interactions with other species: 12
Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
Total fragments: 20375566
Proteins after random average filtering: 44442
Total fragments: 10194077
Proteins after disorder filtering: 31997
Total fragments: 936398
Proteins after pattern filtering: 22949
Total fragments: 302625
Proteins after MINT filtering: 25
Total fragments: 727
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
VPPPVPPRRR |
2.01
|
-12.69 |
0.00 |
| Best peptides |
RRPIVPRRHM |
0.00
|
-9.05 |
3.64 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q62245 |
VPPPVPPRRR |
2.01
|
-14.06 |
-1.37 |
|
GPPVPPRQST |
4.55
|
-9.41 |
3.28 |
|
SPPAIPPRQP |
4.89
|
-12.58 |
0.11 |
| Q02384 |
PAPPVPPRQN |
2.98
|
-10.59 |
2.10 |
|
IPPPLPPRKK |
3.37
|
-12.26 |
0.43 |
|
VPLRPPEHFI |
3.94
|
-8.79 |
3.90 |
| P39054 |
IPPGVPSRRA |
3.59
|
-10.30 |
2.39 |
|
HPPGRPPAVR |
3.82
|
-11.23 |
1.46 |
|
AAPSRPTIIR |
3.83
|
-9.42 |
3.27 |
| P35991 |
KKPLPPEPTA |
5.93
|
-7.81 |
4.88 |
|
KKPLPPTPEE |
7.44
|
-4.93 |
7.76 |
|
LPPTPEEDQI |
7.68
|
-3.84 |
8.85 |
| Q9Z1S8 |
DPLGYPSTAL |
4.94
|
-6.83 |
5.86 |
|
PPPRPPKPSQ |
5.13
|
-8.48 |
4.21 |
|
PRPPKPSQAE |
6.30
|
-7.35 |
5.34 |
| Q62077 |
DCWDGPDGMP |
9.89
|
-4.14 |
8.55 |
|
WDGPDGMPVI |
10.34
|
-2.00 |
10.69 |
| P70424 |
PPPIRPAGAT |
5.00
|
-8.16 |
4.53 |
|
PPIRPAGATL |
5.44
|
-6.34 |
6.35 |
|
TPEGPPPPIR |
5.93
|
-9.03 |
3.66 |
| Q8R550 |
PKKPRPPKTN |
4.13
|
-10.42 |
2.27 |
|
RRPERPVGPL |
5.53
|
-11.00 |
1.69 |
|
ERPVGPLTHT |
5.60
|
-7.37 |
5.32 |
| Q923U0 |
SEPSAPSCDL |
5.40
|
-6.66 |
6.03 |
|
PVPTPNEGAL |
7.72
|
-4.63 |
8.06 |
|
LSPIVPVPTP |
7.83
|
-7.01 |
5.68 |
| O35716 |
AAPVRPRPCP |
6.98
|
-8.10 |
4.59 |
|
SSPAAPVRPR |
7.24
|
-9.56 |
3.13 |
|
PCPAVPAPAP |
7.25
|
-6.85 |
5.84 |
| Q80U87 |
APPSTPPTHK |
5.64
|
-9.14 |
3.55 |
|
PPSTPPTHKV |
5.81
|
-7.97 |
4.72 |
|
VHMYPPEMAP |
6.80
|
-6.30 |
6.39 |
| Q61234 |
SPPASPLQRQ |
5.49
|
-8.77 |
3.92 |
|
GPEPEPAQLN |
6.17
|
-7.56 |
5.13 |
|
EPGPEPEPAQ |
7.44
|
-5.43 |
7.26 |
| Q9JLQ0 |
VPPPPPAAKI |
3.87
|
-9.31 |
3.38 |
|
KKPTAPTKAS |
5.23
|
-7.71 |
4.98 |
|
SPTQSPEKTL |
5.51
|
-6.99 |
5.70 |
| Q60749 |
SPATQPPPLL |
5.39
|
-7.81 |
4.88 |
|
PPPPVPRGRG |
5.46
|
-8.79 |
3.90 |
|
PPPPPVPRGR |
5.83
|
-10.04 |
2.65 |
| Q99JZ7 |
DKPEVPPRVP |
4.14
|
-10.61 |
2.08 |
|
RPPKVPPREP |
4.28
|
-11.69 |
1.00 |
|
SPKSLPSYLN |
4.37
|
-9.87 |
2.82 |
| Q9QUN3 |
KKPATPLKTT |
4.37
|
-9.42 |
3.27 |
|
GPPSVPRRDY |
4.37
|
-9.75 |
2.94 |
|
PPTQKPVHQK |
5.33
|
-7.65 |
5.04 |
| P27870 |
YGIPPPPGAF |
7.22
|
-5.67 |
7.02 |
|
IPPPPGAFGP |
7.78
|
-7.53 |
5.16 |
|
YYGIPPPPGA |
9.05
|
-5.76 |
6.93 |
| P04925 |
NQWNKPSKPK |
9.51
|
-7.16 |
5.53 |
| Q9WU78 |
APPTPAPRTM |
3.50
|
-10.69 |
2.00 |
|
PPPVLPANRV |
4.04
|
-9.01 |
3.68 |
|
NMPYPPVYHQ |
4.90
|
-7.95 |
4.74 |
| Q60992 |
APGAGPGPKM |
6.34
|
-6.91 |
5.78 |
|
NPAPPGKPVL |
6.87
|
-5.81 |
6.88 |
|
PTGRPPSREI |
7.05
|
-7.09 |
5.60 |
| P98083 |
PPPPCPGREL |
2.76
|
-12.19 |
0.50 |
|
LRVPPPPQSM |
3.93
|
-9.90 |
2.79 |
|
VPPPPQSMSM |
6.15
|
-7.38 |
5.31 |
| Q9EQ32 |
RPPRVPPRAA |
3.50
|
-10.84 |
1.85 |
|
NRPPVPVPRP |
5.43
|
-10.16 |
2.53 |
|
GPPPPPDNEP |
5.65
|
-9.30 |
3.39 |
| Q61824 |
RKPSPPQKPL |
5.36
|
-10.92 |
1.77 |
|
KDPGIPGQSI |
5.46
|
-9.27 |
3.42 |
|
GPGAKPAPGI |
5.48
|
-6.79 |
5.90 |
| Q91ZZ2 |
SPPALPPKKR |
3.34
|
-11.12 |
1.57 |
|
PPPALPPKQR |
3.48
|
-10.87 |
1.82 |
|
APPKPPLPGI |
4.12
|
-8.86 |
3.83 |
| Q9QYY0 |
PPKPHPTHDR |
3.92
|
-8.97 |
3.72 |
|
PRPPKPHPTH |
4.51
|
-9.29 |
3.40 |
|
LPPHPDTLGL |
5.37
|
-7.62 |
5.07 |
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