|
Matrix information:
(Help)
ADAN-name: 2DF62.PDB
Scoring matrix: 2DF62_mat
Uniprot code: O55043
Genome source: Rattus norvegicus
Wild-type ligand: PPVIAPRPEHTKSIYTRS
Foldx wt ligand score: 9.34
Foldx random average score for Rattus norvegicus: 22.615 Available information for O55043 in MINT (Nov 2008):
Nš of interacting proteins: 5
Proteins belonging to other specie: 0
Nš of interactions described: 6
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
Total fragments: 5449395
Proteins after random average filtering: 11944
Total fragments: 3141707
Proteins after disorder filtering: 6363
Total fragments: 96132
Proteins after pattern filtering: 4174
Total fragments: 32231
Proteins after MINT filtering: 5
Total fragments: 189
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
PPVIAPRPEHTKSIYTRS |
9.34
|
-22.24 |
0.00 |
| Best peptides |
FEDMWRRRRHRRRRYHKR |
0.00
|
-11.53 |
10.71 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P35465 |
PPAPPMRNTSTMIGAGSK |
17.63
|
-11.29 |
10.95 |
|
VQDKPPAPPMRNTSTMIG |
17.66
|
-10.75 |
11.49 |
|
KPPAPPMRNTSTMIGAGS |
17.84
|
-13.84 |
8.40 |
| Q9QX74 |
TPGAAPRELENHFLGGGE |
18.31
|
-12.14 |
10.10 |
|
LEEEEDREDGDTKPDHSP |
18.46
|
-7.93 |
14.31 |
|
EDVGLGPPAPRMQPSKFP |
18.79
|
-11.38 |
10.86 |
| Q9Z272 |
VPVPSLPSERAEHTLMGP |
19.35
|
-8.75 |
13.49 |
|
PVPVPSLPSERAEHTLMG |
19.52
|
-6.35 |
15.89 |
|
PSLPSERAEHTLMGPGGS |
20.00
|
-13.62 |
8.62 |
| Q9JLU4 |
KPPVPPKPKLKSPLGKGP |
16.49
|
-8.74 |
13.50 |
|
RPKRRPRPSGPDSPYANL |
17.34
|
-14.01 |
8.23 |
|
APPGPLPRSAVGGTLAGG |
17.61
|
-13.73 |
8.51 |
| Q9WV48 |
HPEDAKRQPRGRPSSSGT |
14.83
|
-11.68 |
10.56 |
|
SPDGPGRGPQGTRGRGSG |
16.88
|
-13.13 |
9.11 |
|
PPTLHHHSPHSPHSPHAR |
16.94
|
-12.56 |
9.68 |
|
