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Matrix information:
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ADAN-name: 2C0O3.PDB
Scoring matrix: 2C0O3_mat
Uniprot code: P08631
Genome source: Homo sapiens
Wild-type ligand: MSSKPQKPWEKDA
Foldx wt ligand score: 6.55
Foldx random average score for Homo sapiens: 10.198 Available information for P08631 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 7
Nš of interactions described: 37
Interactions with other species: 17
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 21960385
Proteins after random average filtering: 48021
Total fragments: 11405434
Proteins after disorder filtering: 33029
Total fragments: 527812
Proteins after pattern filtering: 23501
Total fragments: 214097
Proteins after MINT filtering: 7
Total fragments: 159
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
MSSKPQKPWEKDA |
6.55
|
-11.42 |
0.00 |
| Best peptides |
CFGHPGMMDWMRD |
0.00
|
-13.43 |
-2.01 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q92556 |
PDAPPPIPKEPSN |
6.64
|
-11.61 |
-0.19 |
|
DAPPPIPKEPSNY |
10.15
|
-8.77 |
2.65 |
| Q53H12 |
TGPTERPPNEPEE |
9.41
|
-9.37 |
2.05 |
| Q13177 |
EDKPPAPPVRMSS |
6.75
|
-12.17 |
-0.75 |
|
KDGFPSGTPALNA |
8.69
|
-8.56 |
2.86 |
|
PAPPVRMSSTIFS |
9.21
|
-8.85 |
2.57 |
| O43516 |
FSNRPPLPPTPSR |
5.07
|
-12.75 |
-1.33 |
|
SRALPATPQLPSR |
5.27
|
-11.29 |
0.13 |
|
LDDKPPPPPPPVG |
6.78
|
-12.03 |
-0.61 |
| P42768 |
RGGLPPLPLHPGG |
5.44
|
-11.25 |
0.17 |
|
QLPRPPIVGGNKG |
5.80
|
-11.42 |
0.00 |
|
EERRGGLPPLPLH |
5.82
|
-11.99 |
-0.57 |
| P21860 |
SCPLHPVPIMPTA |
5.58
|
-10.93 |
0.49 |
|
LHPVPIMPTAGTT |
6.74
|
-10.85 |
0.57 |
|
PLHPVPIMPTAGT |
8.08
|
-10.32 |
1.10 |
| Q13444 |
PPPRKPLPADPQG |
6.29
|
-11.68 |
-0.26 |
|
KSQGPAKPPPPRK |
6.40
|
-10.96 |
0.46 |
|
GSPLPSWPLPNIG |
6.71
|
-11.41 |
0.01 |
|
