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Matrix information:
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ADAN-name: 2C0I3.PDB
Scoring matrix: 2C0I3_mat
Uniprot code: P08631
Genome source: Homo sapiens
Wild-type ligand: KPQKPWEKD
Foldx wt ligand score: 6.45
Foldx random average score for Homo sapiens: 10.391 Available information for P08631 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 7
Nš of interactions described: 37
Interactions with other species: 17
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22152566
Proteins after random average filtering: 48041
Total fragments: 10871392
Proteins after disorder filtering: 34590
Total fragments: 605386
Proteins after pattern filtering: 24126
Total fragments: 190587
Proteins after MINT filtering: 7
Total fragments: 155
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KPQKPWEKD |
6.45
|
-10.74 |
0.00 |
| Best peptides |
RPEMIDWWW |
0.00
|
-12.44 |
-1.70 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q92556 |
PPPIPKEPS |
8.01
|
-10.98 |
-0.24 |
| Q53H12 |
RPPNEPEET |
9.44
|
-10.69 |
0.05 |
|
TERPPNEPE |
9.56
|
-9.17 |
1.57 |
|
GPTERPPNE |
10.02
|
-9.55 |
1.19 |
| Q13177 |
KPPAPPVRM |
7.22
|
-10.15 |
0.59 |
|
LKPLPSVPE |
7.22
|
-10.55 |
0.19 |
|
PPAPPVRMS |
7.40
|
-10.83 |
-0.09 |
| O43516 |
RPPLPPTPS |
5.16
|
-14.63 |
-3.89 |
|
TPRLPQRNL |
6.01
|
-10.55 |
0.19 |
|
RPPLPPDRP |
6.48
|
-16.34 |
-5.60 |
| P42768 |
PPPLPPALV |
5.80
|
-12.39 |
-1.65 |
|
RRQLPPPPT |
6.03
|
-14.50 |
-3.76 |
|
RGGLPPLPL |
6.26
|
-13.00 |
-2.26 |
| P21860 |
VPIMPTAGT |
6.79
|
-9.49 |
1.25 |
|
HPPRPSSLE |
7.76
|
-11.15 |
-0.41 |
|
CPLHPVPIM |
8.09
|
-10.48 |
0.26 |
| Q13444 |
RKPLPADPQ |
5.26
|
-13.55 |
-2.81 |
|
IPPLVVPSR |
7.22
|
-11.98 |
-1.24 |
|
RPGPPQRAL |
7.35
|
-11.51 |
-0.77 |
|
