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Matrix information:
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ADAN-name: 2BR92.PDB
Scoring matrix: 2BR92_mat
Uniprot code: P62258
Genome source: Homo sapiens
Wild-type ligand: RQRsAP
Foldx wt ligand score: 8.04
Foldx random average score for Homo sapiens: 11.354 Available information for P62258 in MINT (Nov 2008):
Nš of interacting proteins: 23
Proteins belonging to other specie: 2
Nš of interactions described: 39
Interactions with other species: 3
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having weird amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22296734
Proteins after random average filtering: 48052
Total fragments: 11155712
Proteins after disorder filtering: 36997
Total fragments: 908183
Proteins after pattern filtering: 1831
Total fragments: 2113
Proteins after MINT filtering: 3
Total fragments: 4 ROC parameters:
TPR= 0.13
FPR= 0.038
ACC= 0.962
SPC= 0.962
MCC= 0.011 Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
RQRsAP |
8.04
|
-11.99 |
0.00 |
| Best peptides |
yMYEMy |
0.00
|
-12.87 |
-0.88 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q13627 |
RARSDP |
10.24
|
-7.43 |
4.56 |
| Q9Y2U5 |
RDRSSP |
9.80
|
-7.27 |
4.72 |
|
RAQSYP |
9.92
|
-9.22 |
2.77 |
| P30304 |
RDSSEP |
11.10
|
-7.24 |
4.75 |
|
