|
Matrix information:
(Help)
ADAN-name: 2AIN2.PDB
Scoring matrix: 2AIN2_mat
Uniprot code: P55196
Genome source: Homo sapiens
Wild-type ligand: LFSTEV
Foldx wt ligand score: 4.85
Foldx random average score for Homo sapiens: 10.366 Available information for P55196 in MINT (Nov 2008):
Nš of interacting proteins: 18
Proteins belonging to other specie: 0
Nš of interactions described: 30
Interactions with other species: 0
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22296734
Proteins after random average filtering: 48056
Total fragments: 14813850
Proteins after disorder filtering: 38392
Total fragments: 2253472
Proteins after pattern filtering: 29653
Total fragments: 177927
Proteins after MINT filtering: 10
Total fragments: 58
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
LFSTEV |
4.85
|
-2.10 |
0.00 |
| Best peptides |
HMIFMP |
0.00
|
1.22 |
3.32 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P54753 |
SACTTV |
4.53
|
-2.11 |
-0.01 |
|
PGSYKA |
4.84
|
-2.26 |
-0.16 |
|
LTLSWA |
6.94
|
0.02 |
2.12 |
| P11274 |
GAGSSV |
5.27
|
-2.10 |
0.00 |
|
GQSSRV |
5.50
|
-3.29 |
-1.19 |
|
ESKLPA |
5.71
|
-1.35 |
0.75 |
| Q9NQS3 |
PDGLLA |
5.10
|
-1.56 |
0.54 |
|
KCNADA |
6.52
|
-0.09 |
2.01 |
|
SVWSRL |
9.59
|
-1.83 |
0.27 |
| Q15375 |
DGYYRA |
5.09
|
-1.06 |
1.04 |
|
DPPYVA |
6.01
|
-3.52 |
-1.42 |
|
SLKTPL |
8.39
|
-2.97 |
-0.87 |
| Q15796 |
WHPATV |
4.61
|
-2.60 |
-0.50 |
|
NTNFPA |
5.29
|
-0.54 |
1.56 |
|
TTLSPV |
5.96
|
-2.23 |
-0.13 |
| Q15223 |
NGYSKA |
5.24
|
-1.31 |
0.79 |
|
YSKAGI |
8.04
|
-3.12 |
-1.02 |
| Q96NY8 |
PSGVRV |
3.90
|
-4.09 |
-1.99 |
|
PLPSGV |
4.36
|
-4.00 |
-1.90 |
|
SVGLRA |
6.17
|
-0.64 |
1.46 |
| P12931 |
GGAFPA |
4.35
|
-1.72 |
0.38 |
|
SKPASA |
5.50
|
-1.43 |
0.67 |
|
RGPSAA |
6.20
|
0.29 |
2.39 |
| O15197 |
SAAWAV |
4.33
|
-2.55 |
-0.45 |
|
EGFYRA |
4.83
|
-1.55 |
0.55 |
|
PDTLQA |
4.96
|
-1.27 |
0.83 |
| P29323 |
SGTFKA |
4.24
|
-1.99 |
0.11 |
|
PTYTSA |
6.05
|
-0.53 |
1.57 |
|
MPCTTI |
7.95
|
-2.71 |
-0.61 |
|
