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Matrix information:
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ADAN-name: 1ZSG2.PDB
Scoring matrix: 1ZSG2_mat
Uniprot code: Q14155
Genome source: Homo sapiens
Wild-type ligand: PVIAPRPEHTKSVYTRS
Foldx wt ligand score: 9.07
Foldx random average score for Homo sapiens: 18.160 Available information for Q14155 in MINT (Nov 2008):
Nš of interacting proteins: 19
Proteins belonging to other specie: 3
Nš of interactions described: 31
Interactions with other species: 3
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 21768296
Proteins after random average filtering: 48002
Total fragments: 12913236
Proteins after disorder filtering: 30074
Total fragments: 1027935
Proteins after pattern filtering: 22241
Total fragments: 425742
Proteins after MINT filtering: 10
Total fragments: 285
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
PVIAPRPEHTKSVYTRS |
9.07
|
-2.01 |
0.00 |
| Best peptides |
RDIARARAAGWRHHRRG |
0.00
|
-1.61 |
0.40 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q13177 |
EDKPPAPPVRMSSTIFS |
12.56
|
-0.26 |
1.75 |
|
KPPAPPVRMSSTIFSTG |
12.58
|
-1.49 |
0.52 |
|
DPLSANHSLKPLPSVPE |
14.82
|
0.41 |
2.42 |
| Q13153 |
RDVATSPISPTENNTTP |
10.07
|
-1.17 |
0.84 |
|
KPPAPPMRNTSTMIGAG |
13.50
|
-1.25 |
0.76 |
|
SKDAGTLNHGSKPLPPN |
13.92
|
3.28 |
5.29 |
| Q13444 |
LLGAGSPLPSWPLPNIG |
11.45
|
0.92 |
2.93 |
|
KSQGPAKPPPPRKPLPA |
11.50
|
0.81 |
2.82 |
|
ALLARGTKSQGPAKPPP |
11.79
|
-2.34 |
-0.33 |
| Q13191 |
SDGSQAPARPPKPRPRR |
9.62
|
-2.06 |
-0.05 |
|
GSQAPARPPKPRPRRTA |
11.00
|
-0.45 |
1.56 |
|
PPKPRPRRTAPEIHHRK |
11.03
|
-2.54 |
-0.53 |
| P16333 |
LTSGLEPSPPQCDYIRP |
13.13
|
0.58 |
2.59 |
|
PLTSGLEPSPPQCDYIR |
13.28
|
0.73 |
2.74 |
|
KPSVPDSASPADDSFVD |
13.73
|
4.70 |
6.71 |
| P49023 |
GFMAQGKTGSSSPPGGP |
10.27
|
-0.66 |
1.35 |
|
ADEANSSPPLPGALSPL |
10.75
|
2.31 |
4.32 |
|
QGKTGSSSPPGGPPKPG |
11.03
|
2.46 |
4.47 |
| Q9Y2X7 |
SERAEHTPMAPGGSTHR |
9.84
|
-3.71 |
-1.70 |
|
PGPVPTPPLPSERAEHT |
15.17
|
3.38 |
5.39 |
|
PPGPVPTPPLPSERAEH |
15.59
|
2.47 |
4.48 |
| O14936 |
PPTSPYLNGDSPESANG |
13.98
|
1.11 |
3.12 |
|
LRVTPPPTSPYLNGDSP |
14.20
|
2.08 |
4.09 |
|
YGDPPEELPDFSEDPTS |
15.21
|
5.50 |
7.51 |
| Q14161 |
DGLVPDTAEPHVAPSPT |
11.27
|
3.37 |
5.38 |
|
RPMSMYETGSGQKPYLP |
11.84
|
-0.21 |
1.80 |
|
VPDTAEPHVAPSPTLPS |
15.13
|
3.97 |
5.98 |
| Q14160 |
PPWASPSPTSRQSPASP |
9.65
|
-2.43 |
-0.42 |
|
RGGARGHAGNPRDPTDE |
9.89
|
0.44 |
2.45 |
|
GKMAESPCSPSGQQPPS |
10.09
|
0.37 |
2.38 |
|
