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Matrix information:
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ADAN-name: 1ZFP2.PDB
Scoring matrix: 1ZFP2_mat
Uniprot code: P62993
Genome source: Homo sapiens
Wild-type ligand: EyINQ
Foldx wt ligand score: 2.92
Foldx random average score for Homo sapiens: 15.606 Available information for P62993 in MINT (Nov 2008):
Nš of interacting proteins: 64
Proteins belonging to other specie: 6
Nš of interactions described: 157
Interactions with other species: 28
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22344792
Proteins after random average filtering: 48057
Total fragments: 13249503
Proteins after disorder filtering: 38049
Total fragments: 1356683
Proteins after pattern filtering: 17610
Total fragments: 69002
Proteins after MINT filtering: 35
Total fragments: 187
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
EyINQ |
2.92
|
-16.18 |
0.00 |
| Best peptides |
WyDNM |
0.00
|
-15.02 |
1.16 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P05067 |
TDYAD |
14.78
|
-2.98 |
13.20 |
|
YGGCG |
15.29
|
-2.08 |
14.10 |
| O43609 |
YSDNP |
14.04
|
-5.34 |
10.84 |
|
SYSDN |
14.09
|
-3.69 |
12.49 |
| P35968 |
YHSDD |
14.04
|
-4.07 |
12.11 |
|
YQSGY |
15.23
|
-1.42 |
14.76 |
|
GYQSG |
15.36
|
-3.51 |
12.67 |
| Q6S383 |
RYASG |
14.29
|
-5.03 |
11.15 |
|
SPYSV |
14.37
|
-3.29 |
12.89 |
|
YSDPS |
14.50
|
-2.71 |
13.47 |
| O43561 |
YLVVL |
11.94
|
-6.14 |
10.04 |
|
PGYLV |
12.19
|
-6.62 |
9.56 |
|
GYLVV |
12.89
|
-6.64 |
9.54 |
| P21860 |
EYMNR |
8.55
|
-9.21 |
6.97 |
|
YPDVQ |
11.58
|
-3.85 |
12.33 |
|
GYMPM |
12.57
|
-5.44 |
10.74 |
| Q07912 |
AYDDV |
11.23
|
-4.43 |
11.75 |
|
ELYLG |
12.12
|
-8.78 |
7.40 |
|
YDDVA |
12.61
|
-4.14 |
12.04 |
| Q15303 |
DYWNH |
10.83
|
-8.39 |
7.79 |
|
EYHNA |
11.24
|
-6.96 |
9.22 |
|
YPWTG |
13.37
|
-4.68 |
11.50 |
| P00533 |
VYHNQ |
10.78
|
-7.92 |
8.26 |
|
YQMDV |
10.80
|
-5.64 |
10.54 |
|
YQQDF |
12.83
|
-4.57 |
11.61 |
| P62993 |
RNYVT |
14.18
|
-5.87 |
10.31 |
| P22681 |
YDDDD |
11.33
|
-2.43 |
13.75 |
|
NYDDD |
11.51
|
-4.12 |
12.06 |
|
PNYDD |
13.40
|
-4.25 |
11.93 |
| P29353 |
QYYND |
10.80
|
-7.99 |
8.19 |
|
YYNDF |
12.68
|
-5.28 |
10.90 |
| Q13191 |
DYDLL |
8.94
|
-7.32 |
8.86 |
|
YDLLI |
9.79
|
-7.34 |
8.84 |
|
GFYLY |
10.82
|
-8.57 |
7.61 |
| Q13480 |
SLYNL |
9.27
|
-8.74 |
7.44 |
|
YVFNT |
10.64
|
-7.71 |
8.47 |
|
PYQLI |
10.95
|
-8.22 |
7.96 |
| P08729 |
SLYGL |
14.52
|
-4.28 |
11.90 |
| Q13905 |
QYDNI |
8.13
|
-8.25 |
7.93 |
|
SQYDN |
13.30
|
-3.21 |
12.97 |
|
YDNIS |
15.48
|
-3.05 |
13.13 |
| P07949 |
YPNDS |
12.33
|
-3.11 |
13.07 |
|
RYPND |
12.72
|
-6.90 |
9.28 |
|
PGYLG |
12.80
|
-6.14 |
10.04 |
| Q07889 |
SYPLK |
13.99
|
-5.92 |
10.26 |
|
KKYSY |
14.17
|
-3.56 |
12.62 |
|
YSYPL |
15.03
|
-3.22 |
12.96 |
| Q07666 |
EYYDY |
12.65
|
-5.10 |
11.08 |
|
YGQDD |
13.63
|
-4.03 |
12.15 |
|
YSQSQ |
15.16
|
-2.06 |
14.12 |
| Q9UKW4 |
RNYSG |
15.02
|
-3.36 |
12.82 |
| Q9UQC2 |
VYIPM |
13.18
|
-6.11 |
10.07 |
|
GFYSL |
13.63
|
-6.27 |
9.91 |
|
NYVPM |
13.67
|
-5.60 |
10.58 |
| P11137 |
TYSNT |
11.54
|
-7.10 |
9.08 |
|
YPSDL |
12.02
|
-3.20 |
12.98 |
|
YSNTK |
13.10
|
-3.73 |
12.45 |
| P48634 |
PPYLA |
11.46
|
-6.67 |
9.51 |
|
YPEVF |
12.25
|
-4.88 |
11.30 |
|
YPGAL |
13.15
|
-2.82 |
13.36 |
| P48023 |
FNYPY |
14.90
|
-3.27 |
12.91 |
| Q04695 |
YSSCY |
14.18
|
-2.87 |
13.31 |
|
SCYSF |
14.84
|
-3.33 |
12.85 |
|
SYSSC |
15.35
|
-3.81 |
12.37 |
| P27986 |
NGYNE |
11.09
|
-6.00 |
10.18 |
|
YNETT |
12.65
|
-5.71 |
10.47 |
| O43597 |
YPRPL |
13.49
|
-4.23 |
11.95 |
| Q13444 |
HCYCE |
13.45
|
-4.66 |
11.52 |
|
SYVSC |
13.97
|
-4.12 |
12.06 |
|
YCEEG |
14.34
|
-3.46 |
12.72 |
| P05787 |
SYSLG |
12.97
|
-6.22 |
9.96 |
|
YGGLT |
13.02
|
-4.37 |
11.81 |
|
RSYTS |
14.17
|
-5.19 |
10.99 |
| Q8WV28 |
DYENP |
14.06
|
-6.80 |
9.38 |
|
YENPD |
15.29
|
-3.78 |
12.40 |
| P05783 |
SVYAG |
15.20
|
-3.72 |
12.46 |
|
YAGAG |
15.27
|
-1.51 |
14.67 |
| P13987 |
QCYNC |
10.06
|
-7.21 |
8.97 |
|
YNCPN |
15.29
|
-3.73 |
12.45 |
| P04626 |
EYVNQ |
9.77
|
-8.55 |
7.63 |
|
PEYLT |
12.29
|
-8.32 |
7.86 |
|
YYWDQ |
12.76
|
-6.44 |
9.74 |
| Q13094 |
MYIDR |
11.60
|
-6.85 |
9.33 |
|
PYFSQ |
14.49
|
-4.57 |
11.61 |
| P58107 |
YPDPY |
12.24
|
-3.70 |
12.48 |
|
YRDPA |
14.36
|
-3.01 |
13.17 |
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