ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1YWO2.PDB
Scoring matrix: 1YWO2_mat
Uniprot code: P10686
Genome source: Rattus norvegicus
Wild-type ligand: QPPVPPQRPM
Foldx wt ligand score: 3.24
Foldx random average score for Rattus norvegicus: 8.771

Available information for P10686 in MINT (Nov 2008):
Nš of interacting proteins: 3
 Proteins belonging to other specie: 1
Nš of interactions described: 12
 Interactions with other species: 3

Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
 Total fragments: 5544981
Proteins after random average filtering: 11947
 Total fragments: 2536265
Proteins after disorder filtering: 8629
 Total fragments: 186478
Proteins after pattern filtering: 6101
 Total fragments: 74089
Proteins after MINT filtering: 2
 Total fragments: 129


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

QPPVPPQRPM

3.24

-13.42

0.00

Best peptides

IRPWPFHRRA

0.00

-12.69

0.73

         
Interactors      
Q8CGU4

PAPASPARPV

4.17

-10.77

2.65

PRDPGSPRGA

4.59

-10.90

2.52

PLPGPQGLSS

4.70

-9.86

3.56

Q63537

GKVLPPRRLP

2.00

-13.80

-0.38

ASPGPERRPP

3.41

-12.12

1.30

SSKTPPQRPA

4.15

-12.03

1.39

 


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