ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1YBO2.PDB
Scoring matrix: 1YBO2_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: TNEFYA
Foldx wt ligand score: 5.17
Foldx random average score for Homo sapiens: 9.956

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22296734
Proteins after random average filtering: 48054
 Total fragments: 12891668
Proteins after disorder filtering: 38008
 Total fragments: 1626391
Proteins after pattern filtering: 28208
 Total fragments: 146595
Proteins after MINT filtering: 1
 Total fragments: 4


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

TNEFYA

5.17

-10.21

0.00

Best peptides

WGMFMA

0.00

-11.63

-1.42

         
Interactors      
P30203

QPAFSA

5.41

-7.50

2.71

SPKSKL

6.15

-8.07

2.14

PTTIPA

7.31

-7.65

2.56

 


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