ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1WLP3.PDB
Scoring matrix: 1WLP3_mat
Uniprot code: P13498
Genome source: Homo sapiens
Wild-type ligand: PPSNPPPRPPA
Foldx wt ligand score: 4.59
Foldx random average score for Homo sapiens: 9.695

Available information for P13498 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22056464
Proteins after random average filtering: 48037
 Total fragments: 10228758
Proteins after disorder filtering: 34608
 Total fragments: 902192
Proteins after pattern filtering: 25638
 Total fragments: 401076
Proteins after MINT filtering: 1
 Total fragments: 6


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

PPSNPPPRPPA

4.59

-6.69

0.00

Best peptides

FMDMIWKRKRR

0.00

-6.73

-0.04

         
Interactors      
P14598

PQPAVPPRPSA

5.03

-5.51

1.18

QPAVPPRPSAD

7.78

-4.86

1.83

SKPQPAVPPRP

8.43

-4.57

2.12

 


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