ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1WLP2.PDB
Scoring matrix: 1WLP2_mat
Uniprot code: P13498
Genome source: Homo sapiens
Wild-type ligand: KQPPSNPPPRPPAEARKK
Foldx wt ligand score: 6.42
Foldx random average score for Homo sapiens: 16.644

Available information for P13498 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 2
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 21720287
Proteins after random average filtering: 47995
 Total fragments: 11226972
Proteins after disorder filtering: 28440
 Total fragments: 834348
Proteins after pattern filtering: 21178
 Total fragments: 388848
Proteins after MINT filtering: 1
 Total fragments: 1


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

KQPPSNPPPRPPAEARKK

6.42

-12.90

0.00

Best peptides

FHIPRRFPKDQLHRMKHY

0.00

-9.81

3.09

         
Interactors      
P14598

FLEPLDSPDETEDPEPNY

11.53

-7.88

5.02

 


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