ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1W9O2.PDB
Scoring matrix: 1W9O2_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: NEYYV
Foldx wt ligand score: 4.13
Foldx random average score for Homo sapiens: 8.356

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22344792
Proteins after random average filtering: 48056
 Total fragments: 14374693
Proteins after disorder filtering: 38366
 Total fragments: 1211358
Proteins after pattern filtering: 29598
 Total fragments: 164793
Proteins after MINT filtering: 1
 Total fragments: 6


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

NEYYV

4.13

-11.15

0.00

Best peptides

FIFFR

0.00

-11.57

-0.42

         
Interactors      
P30203

TTIPA

6.00

-8.15

3.00

PKSKL

6.50

-8.05

3.10

PAFSA

6.51

-6.66

4.49

 


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