ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1U382.PDB
Scoring matrix: 1U382_mat
Uniprot code: Q02410
Genome source: Homo sapiens
Wild-type ligand: PVYI
Foldx wt ligand score: 3.9
Foldx random average score for Homo sapiens: 6.466

Available information for Q02410 in MINT (Nov 2008):
Nš of interacting proteins: 4
 Proteins belonging to other specie: 0
Nš of interactions described: 9
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22392853
Proteins after random average filtering: 48058
 Total fragments: 12185642
Proteins after disorder filtering: 38189
 Total fragments: 1191350
Proteins after pattern filtering: 30377
 Total fragments: 182964
Proteins after MINT filtering: 4
 Total fragments: 28


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

PVYI

3.90

-7.25

0.00

Best peptides

MGYM

0.00

-0.84

6.41

         
Interactors      
Q00975

NTIV

4.21

-6.75

0.50

SSAV

4.24

-5.16

2.09

TVTV

4.65

-4.68

2.57

P49768

MTEL

4.00

-4.94

2.31

PAPL

5.18

-6.07

1.18

ELPA

5.89

-4.44

2.81

Q02410

YVEV

4.04

-5.47

1.78

GLQA

4.97

-3.20

4.05

PVEA

5.21

-3.27

3.98

O14618

LSKI

5.72

-3.79

3.46

 


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