ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1TP32.PDB
Scoring matrix: 1TP32_mat
Uniprot code: P31016
Genome source: Rattus norvegicus
Wild-type ligand: KKETPV
Foldx wt ligand score: 4.85
Foldx random average score for Rattus norvegicus: 11.004

Available information for P31016 in MINT (Nov 2008):
Nš of interacting proteins: 55
 Proteins belonging to other specie: 18
Nš of interactions described: 141
 Interactions with other species: 34

Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
 Total fragments: 5592797
Proteins after random average filtering: 11953
 Total fragments: 3418369
Proteins after disorder filtering: 9306
 Total fragments: 259780
Proteins after pattern filtering: 6929
 Total fragments: 30308
Proteins after MINT filtering: 28
 Total fragments: 228


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

KKETPV

4.85

-9.56

0.00

Best peptides

GGDMMV

0.00

-10.53

-0.97

         
Interactors      
P19814

NKTTGV

6.02

-10.57

-1.01

SGNTSA

6.76

-5.47

4.09

KPTSKV

9.47

-10.04

-0.48

Q6IN36

GGLFQA

7.60

-7.13

2.43

GRATSA

7.85

-5.54

4.02

QRNLSL

8.18

-11.21

-1.65

Q8R4T5

SAETPA

7.39

-7.03

2.53

FGPLLA

7.61

-5.59

3.97

ETPASV

7.63

-7.18

2.38

Q63226

NDDYTL

7.24

-10.57

-1.01

FFRSPI

8.73

-7.73

1.83

TLGLNL

9.16

-10.49

-0.93

Q62765

PLRITV

5.13

-9.94

-0.38

PKPVMV

5.93

-10.44

-0.88

NTITMI

6.18

-10.99

-1.43

P15385

GGYSSV

6.52

-8.56

1.00

LNDTSA

6.68

-6.49

3.07

CSYTDL

10.21

-8.32

1.24

Q71RJ2

RDASPV

7.61

-9.19

0.37

ASPVGV

9.52

-6.61

2.95

Q9WV48

GRSMSV

4.52

-10.92

-1.36

GLPLLV

5.09

-12.04

-2.48

GGGAGV

5.66

-8.22

1.34

Q8K430

SPTLSV

8.58

-8.90

0.66

DGSSSL

10.01

-9.22

0.34

Q9QX19

RGRLPA

8.27

-6.16

3.40

VASSPA

10.71

-5.00

4.56

Q00960

PLDIGL

6.06

-10.61

-1.05

ANKSSV

6.52

-8.26

1.30

KKPLDI

7.60

-11.71

-2.15

Q9JJ40

VKEAPA

7.20

-5.65

3.91

EAPAPI

7.24

-6.60

2.96

PAPISA

7.45

-4.39

5.17

P11506

AIDSGI

7.47

-8.28

1.28

GLQLPA

7.50

-7.60

1.96

DGAAPA

7.66

-6.43

3.13

P97924

ARDSAV

5.97

-10.31

-0.75

PYQFRV

6.31

-9.09

0.47

GEPTEA

7.99

-6.09

3.47

P30937

PATLPL

9.29

-8.99

0.57

TPGINA

10.11

-4.17

5.39

P05696

KHKFKI

8.56

-8.94

0.62

Q9WUL3

QGSYMV

3.47

-9.59

-0.03

GSYMVV

6.35

-9.65

-0.09

GKKARL

7.24

-10.88

-1.32

Q9QUH6

PGDTFA

4.77

-8.67

0.89

KDLFYV

5.28

-12.35

-2.79

DLSTGV

6.45

-8.45

1.11

P70587

DKGIFV

3.60

-10.20

-0.64

IFVTRV

5.33

-10.45

-0.89

TRPTPV

6.12

-8.97

0.59

P20595

DPQFHL

10.36

-10.52

-0.96

Q9Z1T4

CLNAPV

4.57

-7.44

2.12

LQDLYI

4.68

-13.21

-3.65

HCCLNA

8.29

-7.57

1.99

Q62936

YGDWQV

5.30

-10.85

-1.29

DPGIFI

7.45

-11.36

-1.80

GLGFSI

7.94

-6.75

2.81

P97836

DGDMCL

5.01

-11.16

-1.60

GNHYHA

6.53

-7.03

2.53

YLLSPV

6.61

-7.49

2.07

P35439

VGNTNI

5.55

-9.76

-0.20

FTPTPV

7.94

-8.77

0.79

Q63622

EYKTSL

7.38

-10.54

-0.98

DPGIFI

7.45

-11.36

-1.80

GLGFSI

7.94

-6.75

2.81

Q62868

MDSSSI

9.09

-7.50

2.06

P29476

PWNTHV

3.98

-10.29

-0.73

PKTIRV

4.58

-10.64

-1.08

VPCILV

6.30

-9.68

-0.12

Q00959

KGDSTL

8.65

-9.96

-0.40

GNKSSL

9.03

-8.87

0.69

SCLSNL

9.58

-9.31

0.25

 


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