ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1SSH2.PDB
Scoring matrix: 1SSH2_mat
Uniprot code: P43603
Genome source: Saccharomyces cerevisiae
Wild-type ligand: GPPPAMPARPT
Foldx wt ligand score: 4.04
Foldx random average score for Saccharomyces cerevisiae: 16.995

Available information for P43603 in MINT (Nov 2008):
Nš of interacting proteins: 108
 Proteins belonging to other specie: 0
Nš of interactions described: 170
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Saccharomyces cerevisiae: 7409
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 230
Total scanned proteins: 7179
 Total fragments: 3193184
Proteins after random average filtering: 7178
 Total fragments: 1553219
Proteins after disorder filtering: 4427
 Total fragments: 90236
Proteins after pattern filtering: 2282
 Total fragments: 21499
Proteins after MINT filtering: 75
 Total fragments: 1196


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

GPPPAMPARPT

4.04

-18.10

0.00
Best peptides

FDRPRMPRRRR

0.00

-20.19

-2.09
         
Interactors      
P38140

NIQPDLPPRKI

3.84

-19.19

-1.09

IQPDLPPRKIM

12.33

-10.72

7.38

ANIPPHPYPSS

12.41

-9.93

8.17
Q06604

EEKPLLPTRPN

3.59

-18.19

-0.09

SSPPPLPTRRD

3.92

-19.96

-1.86

EKGPRMPSRGR

4.76

-18.10

0.00
P09119

AQVPLTPTTSP

12.75

-9.13

8.97

PLTPTTSPVKK

13.27

-9.15

8.95

LTPTTSPVKKS

13.56

-8.68

9.42
P24814

DIHPNLGPQLW

11.94

-10.25

7.85

SNRLHPPDIHP

12.00

-10.24

7.86

NNNSTRPQMPS

12.93

-9.76

8.34
P25604

QNTPPLPPKPK

9.04

-14.30

3.80

DQAPSLPPKPN

9.49

-14.07

4.03

HLKPPLPPPPP

9.85

-13.65

4.45
P40956

TSTPPLPRRRA

3.20

-20.07

-1.97

TTSTPPLPRRR

11.19

-11.30

6.80

AATTSTPPLPR

11.52

-10.25

7.85
P25623

SDTPPLPPHAT

10.30

-12.29

5.81

SKTKPLPVEPA

12.22

-10.99

7.11

KPLPVEPASPS

12.31

-10.47

7.63
Q12532

PFKPYINGGDT

14.68

-7.43

10.67
P50942

VPRPCPPIRRK

3.46

-18.55

-0.45

LPPPPPTSRHN

9.24

-14.51

3.59

PRPCPPIRRKS

10.65

-14.54

3.56
Q04322

STPPTLPPRRI

3.79

-19.72

-1.62

KNDQAPLDRPQ

12.97

-9.32

8.78

NATPSKSPTSA

13.87

-7.59

10.51
P38266

FQPPPKPFRRS

3.75

-19.97

-1.87

GGQPPVPVRMQ

3.99

-18.68

-0.58

FLPPPKPFRHT

4.57

-18.06

0.04
P47043

SKPPQLPPKCS

10.21

-12.76

5.34

MHLESKPPQLP

11.29

-11.68

6.42

PQLPPKCSSLR

11.36

-12.25

5.85
P15891

AAQPPLPSRNV

4.33

-19.03

-0.93

SAAPPPPPRRA

5.42

-18.87

-0.77

AAPPPPPRRAT

6.44

-17.18

0.92
P40341

PPPPPKPPLND

11.06

-13.41

4.69

PPPPPPPPKPP

11.10

-13.39

4.71

RNIPPPPPPPP

11.90

-12.51

5.59
Q12134

STHQPVPSPMN

12.65

-9.99

8.11

THQPVPSPMNS

13.38

-8.85

9.25

HQPVPSPMNSQ

15.57

-8.54

9.56
P40494

GKDKSRPPRPP

6.39

-13.76

4.34

KSRPPRPPPKP

9.51

-12.95

5.15

SRPPRPPPKPL

10.55

-14.04

4.06
Q12200

VCPPSFPSRRC

5.42

-18.16

-0.06

NELPCPVPRSF

8.55

-14.63

3.47

GNELPCPVPRS

12.14

-11.39

6.71
Q12344

TSSPPLPPRQN

5.11

-17.72

0.38

STSPKLPPRGK

5.46

-16.67

1.43

PKLPPRGKQRE

11.43

-11.92

6.18
P53189

PTSTLQPSTIP

13.34

-7.87

10.23

TSTLQPSTIPQ

15.01

-6.82

11.28
P53238

AGRPIPPAPTH

10.96

-9.98

8.12

RPIPPAPTHYN

11.73

-12.88

5.22

PAGRPIPPAPT

12.77

-9.80

8.30
P32660

GYDPTDPNRPK

6.30

-14.83

3.27

PTDPNRPKVTK

11.02

-9.77

8.33

FHGDGHAPMSP

15.04

-7.04

11.06
P33400

QILPPLPVGIS

10.21

-12.57

5.53

TSPQILPPLPV

11.52

-10.80

7.30

VQPPNAPSYQS

12.40

-9.84

8.26
P53901

PPLPPIPTRDD

5.80

-17.53

0.57

YNQPPLPPIPT

9.09

-13.44

4.66

LNSPKLPPLPT

9.59

-12.22

5.88
P38739

GSPPNDPSTLA

12.36

-9.85

8.25

ASPFHDPILPR

13.60

-8.47

9.63

FTTTSPSTAPS

15.00

-6.47

11.63
Q04749

SPLPVLPRRIS

3.31

-19.10

-1.00

ITNPVFNPRKP

8.66

-14.48

3.62

VFNPRKPTLST

10.71

-12.01

6.09
P04051

FQDRSLPHFPK

10.31

-11.98

6.12

RSLPHFPKNSK

12.55

-10.08

8.02

PHFPKNSKTPQ

12.95

-9.05

9.05
P43603

QGRFTAPTSPS

13.07

-9.01

9.09

FTAPTSPSTSS

14.46

-8.04

10.06

SQGRFTAPTSP

15.99

-5.87

12.23
P40528

NDIPITPSHDN

12.01

-9.64

8.46

SSLNDIPITPS

12.90

-8.98

9.12

PITPSHDNNPH

14.96

-7.85

10.25
P40325

QSQPPRPPRPA

3.97

-16.83

1.27

SSQPRPPPRPQ

4.57

-17.72

0.38

SLPWTYPPRFY

7.98

-14.30

3.80
P47129

SGPPLLPPRNT

5.51

-18.32

-0.22

NINNTLPNRKP

7.30

-16.56

1.54

RKPNPPPNRSQ

9.90

-14.66

3.44
P40453

WKPPDLPIRLR

3.62

-19.27

-1.17

IRLRKRPPPPP

10.86

-12.00

6.10

VSMPTTPEIPP

10.86

-10.94

7.16
P40095

LPPPRSPNRPT

6.79

-17.53

0.57

RIPVLPPPRSP

8.74

-14.96

3.14

NRIPVLPPPRS

9.35

-13.36

4.74
Q12168

RGPPPLPPRAN

5.56

-18.05

0.05

NDDPYFPQFRS

11.30

-12.42

5.68

PPLPPRANVQP

11.49

-10.82

7.28
P36125

LPAGPQGQRRR

9.70

-12.52

5.58

PAGPQGQRRRN

11.78

-12.18

5.92

NDLPAGPQGQR

12.69

-9.49

8.61
P32793

GHGPTHPSNMS

11.49

-8.34

9.76

YSLGHGPTHPS

13.40

-9.47

8.63

GYSLGHGPTHP

15.51

-5.87

12.23
P36122

PDLPSTIKPLA

14.35

-8.86

9.24
P36123

YTTPKTPPRPK

5.18

-18.18

-0.08

FPPDHFPSRSQ

8.68

-14.11

3.99

YARPGNPLYTT

10.91

-10.14

7.96
Q08412

DVPPQLPTRTK

5.09

-17.31

0.79

IELPTQPVRKN

5.31

-17.75

0.35

KWQPLPPEPLD

11.41

-10.61

7.49
Q06697

NGSSGGPRKDP

15.64

-6.48

11.62
Q06409

TGKPRKTPRPP

6.31

-15.16

2.94

PRKTPRPPFPF

10.64

-11.58

6.52

DISTGKPRKTP

11.20

-9.68

8.42
P32634

ETVPTEPTRYN

6.80

-15.82

2.28

IPLEPLPPVPK

10.70

-12.99

5.11

PNSPILPVLNI

10.71

-11.70

6.40
Q06833

SNRRPVPRRPS

4.50

-18.48

-0.38

ISNRRPVPRRP

8.03

-16.34

1.76

RPVPRRPSQPL

10.35

-12.50

5.60
P53118

ENPHDLPSHLG

11.58

-10.07

8.03

NPHDLPSHLGS

15.53

-6.04

12.06
Q12199

TAAPATPPRHI

6.16

-16.23

1.87

CNNPNNPQCLH

12.53

-10.30

7.80

AAPATPPRHIC

13.07

-8.48

9.62
P19158

EYDPSLPDTPT

10.58

-11.18

6.92

SMTPVSPLGLD

13.73

-8.63

9.47

SSMTPVSPLGL

14.19

-8.26

9.84
P38870

PTTPERPKRKS

4.76

-17.51

0.59

SSTPTTPERPK

5.76

-17.41

0.69

HSTPKPPPNDK

13.01

-9.61

8.49
P43638

VPTNIPPPRGR

9.20

-14.04

4.06

PDAPKLPSAFR

10.57

-11.56

6.54

PPHPDAPKLPS

10.99

-11.01

7.09
P53933

VAPPPLPNRQL

4.98

-18.38

-0.28

RRRPPPPPIPS

10.39

-12.39

5.71

AKRVAPPPLPN

10.51

-11.26

6.84
P50101

TVFPGSPIDKS

13.01

-9.26

8.84

SIGTVFPGSPI

14.39

-7.22

10.88

IGTVFPGSPID

15.73

-5.82

12.28
P40020

SEEPTSPTRQV

7.77

-15.48

2.62

RVLPPLPFPLY

9.65

-13.95

4.15

KKSRVLPPLPF

10.49

-10.67

7.43
P38238

LDPVQSPTNPP

14.30

-9.24

8.86

SLDPVQSPTNP

15.27

-7.72

10.38

PVQSPTNPPYK

16.32

-7.46

10.64
P00175

PELVCPPYAPG

12.47

-8.76

9.34

RFLPNHPGGQD

12.55

-9.48

8.62

PPELVCPPYAP

13.15

-8.92

9.18
Q08229

DYNPTIPPRSK

6.33

-16.14

1.96

PSTPNEDSRVT

10.57

-11.55

6.55

YLTRPLPSTPN

10.85

-10.84

7.26
P38930

QAFPDMVPKHP

10.31

-12.97

5.13

AFPDMVPKHPT

12.34

-9.94

8.16
Q12446

RPLPQLPNRNN

4.86

-18.50

-0.40

LPAPPPPPRRG

5.39

-18.88

-0.78

PAPPPPPHRHV

5.84

-16.57

1.53
P32855

GATNNAPTLPK

13.47

-9.08

9.02

NGATNNAPTLP

14.68

-6.44

11.66

DLNYSNPSSSP

15.90

-6.66

11.44
Q12211

DKRPKSGPRLD

7.45

-15.14

2.96

IDKRPKSGPRL

12.05

-9.05

9.05

HGMQYNPPNPT

13.10

-9.13

8.97
Q06116

PNSPELVPRSS

7.85

-15.17

2.93

GVKPFYPVTSE

12.74

-8.76

9.34

DGNGVKPFYPV

12.75

-9.49

8.61
P33336

PPDRNLPSHPS

10.48

-11.01

7.09

RNLPSHPSSNN

12.83

-10.56

7.54

TSITCDPEDYP

14.44

-6.99

11.11
P40041

PLSPPSSSNMG

14.54

-8.62

9.48

KIPLSPPSSSN

15.19

-7.22

10.88
P38090

VCSPNDPDLTA

12.96

-8.62

9.48

PNDPDLTAAIN

13.70

-8.39

9.71

GIVCSPNDPDL

16.95

-4.91

13.19
Q06266

SQFPSSPYRTV

7.07

-15.91

2.19

PSSPAFPGQLA

11.91

-9.60

8.50

DAIPSSPAFPG

12.41

-10.06

8.04
Q00916

KPRPPLSYKRP

9.08

-13.11

4.99

PTDYPYAKRQT

9.27

-14.05

4.05

VSRLFKPRPPL

10.15

-11.68

6.42
P07269

NASDSGPQRPK

8.08

-14.20

3.90

SELPNTPDFLK

10.46

-11.56

6.54

PTDSELPNTPD

13.15

-8.71

9.39
P40563

PKRRAPPPVPK

10.58

-11.48

6.62

RAPPPVPKKPS

11.03

-13.47

4.63

KRRAPPPVPKK

12.37

-10.26

7.84
P10566

RPIPAIPMDLP

11.26

-11.60

6.50

STRPIPAIPMD

11.40

-10.03

8.07

NSTRPIPAIPM

11.78

-11.32

6.78
P38289

NHMYDVPTNDP

13.69

-7.51

10.59

DVPTNDPSGIL

14.40

-6.40

11.70

PENPSFINYRF

14.83

-8.50

9.60
P47030

MDTETKPPRAP

7.02

-15.51

2.59

EAFPPEPSMSS

11.64

-11.27

6.83

STDEAFPPEPS

14.30

-7.64

10.46
P32790

GPPPAMPARPT

4.04

-18.50

-0.40

PIKPPRPTSTT

11.47

-10.84

7.26

APAPLDPFKTG

12.53

-9.36

8.74
P32863

PDRPPNGIGAG

14.31

-7.69

10.41

LPDRPPNGIGA

16.09

-6.76

11.34
P32862

NTVPSTPSRSN

6.87

-16.21

1.89

SSPGSTPQRST

9.53

-12.77

5.33

GGQPQLPPPQQ

10.32

-11.81

6.29
P39743

PPAYSNPLTSP

15.31

-6.52

11.58

DPNATIPEDNP

15.33

-7.69

10.41

AYSNPLTSPVA

16.53

-6.12

11.98
P31374

FEQPRLPSTAS

9.61

-12.35

5.75

YGNNISPERPS

9.92

-14.05

4.05

ISPERPSFRQP

9.94

-12.07

6.03
P53169

PIMPTLPPRPY

3.14

-19.49

-1.39

NSVPIMPTLPP

9.18

-13.07

5.03

NTANSVPIMPT

13.54

-8.79

9.31
P53955

AQRNPIPYPID

12.28

-9.62

8.48

YDSNQNDPRSP

13.58

-9.80

8.30

SLAQRNPIPYP

14.55

-9.18

8.92

 


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