ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1RZX2.PDB
Scoring matrix: 1RZX2_mat
Uniprot code: O97111
Genome source: Drosophila melanogaster
Wild-type ligand: VKESLV
Foldx wt ligand score: 3.29
Foldx random average score for Drosophila melanogaster: 10.551

Available information for O97111 in MINT (Nov 2008):
Nš of interacting proteins: 14
 Proteins belonging to other specie: 1
Nš of interactions described: 19
 Interactions with other species: 3

Genome scanning information:
Subcellular location: False
Proteins in genome Drosophila melanogaster: 30509
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 4389
Total scanned proteins: 26120
 Total fragments: 13409239
Proteins after random average filtering: 26120
 Total fragments: 7471726
Proteins after disorder filtering: 20110
 Total fragments: 579928
Proteins after pattern filtering: 15498
 Total fragments: 91712
Proteins after MINT filtering: 6
 Total fragments: 73


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

VKESLV

3.29

-15.22

0.00

Best peptides

IWIMLV

0.00

-17.02

-1.80

         
Interactors      
Q9VB22

VPEAAV

6.60

-11.91

3.31

VSSLGL

7.17

-9.54

5.68

ENVSSL

7.41

-11.14

4.08

Q9VA70

GYSFAA

8.22

-6.45

8.77

FCSSNL

8.88

-10.22

5.00

GKFVGA

9.20

-8.29

6.93

P16371

PPDALV

5.35

-14.22

1.00

ASCIDI

6.12

-12.20

3.02

GATMGL

6.97

-11.29

3.93

Q9VCU7

NREVPI

5.24

-15.06

0.16

GPAISA

9.09

-7.53

7.69

Q8WRS3

PMSMPV

4.84

-13.08

2.14

NLGMVV

4.99

-12.69

2.53

SRGSLL

5.09

-13.14

2.08

O96782

NYAVNI

6.32

-12.09

3.13

TPHIEV

6.37

-12.41

2.81

APPIPV

6.58

-13.32

1.90

 


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