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Matrix information:
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ADAN-name: 1RGR2.PDB
Scoring matrix: 1RGR2_mat
Uniprot code: P31016
Genome source: Rattus norvegicus
Wild-type ligand: YKKTEV
Foldx wt ligand score: 5.06
Foldx random average score for Rattus norvegicus: 9.299 Available information for P31016 in MINT (Nov 2008):
Nš of interacting proteins: 55
Proteins belonging to other specie: 18
Nš of interactions described: 141
Interactions with other species: 34
Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
Total fragments: 5592797
Proteins after random average filtering: 11954
Total fragments: 3607804
Proteins after disorder filtering: 9453
Total fragments: 359104
Proteins after pattern filtering: 7261
Total fragments: 37372
Proteins after MINT filtering: 29
Total fragments: 282
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
YKKTEV |
5.06
|
-4.69 |
0.00 |
| Best peptides |
WMMQDI |
0.00
|
-3.04 |
1.65 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P19814 |
PPGVDI |
4.94
|
-4.03 |
0.66 |
|
DSDFSL |
6.15
|
-2.06 |
2.63 |
|
KPTSKV |
6.23
|
-3.86 |
0.83 |
| Q6IN36 |
PPTFAL |
5.51
|
-3.14 |
1.55 |
|
PGRFPA |
5.65
|
-3.52 |
1.17 |
|
ARALPA |
5.73
|
-2.45 |
2.24 |
| Q8R4T5 |
FGPLLA |
5.25
|
-2.36 |
2.33 |
|
GPLLAA |
5.46
|
-3.39 |
1.30 |
|
ETPASV |
6.29
|
-0.95 |
3.74 |
| Q63226 |
FFRSPI |
4.54
|
-2.20 |
2.49 |
|
KTMSSI |
5.08
|
-2.07 |
2.62 |
|
NDDYTL |
6.41
|
-2.46 |
2.23 |
| Q62765 |
PVMVYI |
3.40
|
-6.34 |
-1.65 |
|
GDPLRI |
4.52
|
-4.25 |
0.44 |
|
NTITMI |
4.76
|
-4.43 |
0.26 |
| P15385 |
CSYTDL |
6.03
|
-3.16 |
1.53 |
|
PHCSDL |
6.26
|
-2.45 |
2.24 |
|
GGYSSV |
6.92
|
-1.51 |
3.18 |
| Q71RJ2 |
ASPVGV |
6.32
|
-3.40 |
1.29 |
|
RDASPV |
6.78
|
-0.93 |
3.76 |
| Q9WV48 |
PGLFDI |
3.07
|
-5.05 |
-0.36 |
|
DPFAPV |
4.38
|
-2.33 |
2.36 |
|
GEFLFA |
4.69
|
-3.72 |
0.97 |
| Q8K430 |
SPTLSV |
5.14
|
-1.88 |
2.81 |
|
DGSSSL |
8.11
|
-0.63 |
4.06 |
| Q9QX19 |
RGRLPA |
6.21
|
-2.81 |
1.88 |
|
VASSPA |
8.20
|
0.51 |
5.20 |
| Q00960 |
KKPLDI |
3.82
|
-2.89 |
1.80 |
|
ANKSSV |
5.88
|
-2.60 |
2.09 |
|
GSTSSI |
6.19
|
-0.87 |
3.82 |
| Q9JJ40 |
EAPAPI |
5.27
|
-3.83 |
0.86 |
|
SAPLEA |
6.13
|
-0.99 |
3.70 |
|
PISAPL |
6.90
|
-1.89 |
2.80 |
| P11506 |
AIDSGI |
5.59
|
-2.22 |
2.47 |
|
GLQLPA |
5.92
|
-2.45 |
2.24 |
|
SPGSPI |
6.60
|
0.29 |
4.98 |
| P97924 |
PPPMKI |
3.58
|
-4.26 |
0.43 |
|
GDKFDA |
4.66
|
-3.84 |
0.85 |
|
PYQFRV |
4.95
|
-6.05 |
-1.36 |
| P30937 |
PATLPL |
5.40
|
-3.74 |
0.95 |
|
NTPATL |
7.46
|
-1.34 |
3.35 |
|
TPGINA |
7.83
|
0.23 |
4.92 |
| P05696 |
KHKFKI |
4.32
|
-3.36 |
1.33 |
|
DPYVKL |
6.22
|
-3.85 |
0.84 |
| Q9WUL3 |
GSYMVV |
4.87
|
-5.51 |
-0.82 |
|
QGSYMV |
5.33
|
-4.54 |
0.15 |
|
KARLQL |
6.22
|
-4.12 |
0.57 |
| Q9QUH6 |
KDLFYV |
4.34
|
-2.84 |
1.85 |
|
MDMARL |
4.62
|
-5.02 |
-0.33 |
|
PPQITI |
5.21
|
-5.06 |
-0.37 |
| P70587 |
WNPYPL |
4.77
|
-3.80 |
0.89 |
|
GLGFSI |
5.32
|
-2.05 |
2.64 |
|
DKGIFV |
5.59
|
-4.86 |
-0.17 |
| P20595 |
DPQFHL |
5.83
|
-1.59 |
3.10 |
| Q9Z1T4 |
LQDLYI |
5.10
|
-4.86 |
-0.17 |
|
CLNAPV |
5.48
|
-2.04 |
2.65 |
|
HCCLNA |
5.80
|
-2.38 |
2.31 |
| Q62936 |
DPGIFI |
4.77
|
-3.31 |
1.38 |
|
GLGFSI |
5.32
|
-2.05 |
2.64 |
|
YGDWQV |
5.42
|
-4.47 |
0.22 |
| P97836 |
YLLSPV |
5.20
|
-3.67 |
1.02 |
|
DGDMCL |
5.62
|
-2.47 |
2.22 |
|
HKPYLL |
6.58
|
-4.48 |
0.21 |
| P35439 |
FTPTPV |
5.63
|
-1.93 |
2.76 |
|
VGNTNI |
6.14
|
-1.65 |
3.04 |
| Q63622 |
DPGIFI |
4.77
|
-3.31 |
1.38 |
|
GLGFSI |
5.32
|
-2.05 |
2.64 |
|
GRYSPI |
5.89
|
-3.04 |
1.65 |
| Q62868 |
MDSSSI |
5.57
|
-2.56 |
2.13 |
| P29476 |
VPCILV |
5.39
|
-5.75 |
-1.06 |
|
PKTIRV |
5.68
|
-6.81 |
-2.12 |
|
GDHLGV |
5.71
|
-3.88 |
0.81 |
| Q00959 |
EPSFHL |
6.69
|
-1.02 |
3.67 |
|
SCLSNL |
7.18
|
-0.79 |
3.90 |
|
GNKSSL |
7.46
|
-2.12 |
2.57 |
| Q9WVI4 |
CPLSKL |
6.21
|
-3.09 |
1.60 |
|
PPGSRA |
7.91
|
-0.27 |
4.42 |
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