ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1R1P2.PDB
Scoring matrix: 1R1P2_mat
Uniprot code: O89100
Genome source: Mus musculus
Wild-type ligand: DDyVNV
Foldx wt ligand score: 3.37
Foldx random average score for Mus musculus: 18.129

Available information for O89100 in MINT (Nov 2008):
Nš of interacting proteins: 14
 Proteins belonging to other specie: 8
Nš of interactions described: 28
 Interactions with other species: 14

Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
 Total fragments: 20553348
Proteins after random average filtering: 44446
 Total fragments: 10910782
Proteins after disorder filtering: 33741
 Total fragments: 782455
Proteins after pattern filtering: 15662
 Total fragments: 71468
Proteins after MINT filtering: 6
 Total fragments: 46


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

DDyVNV

3.37

-17.76

0.00

Best peptides

yDyyNM

0.00

-17.81

-0.05

         
Interactors      
Q9QUN3

SDYENP

12.55

-10.49

7.27

DYENPD

15.49

-4.55

13.21

GDDSYE

17.38

5.25

23.01

P70218

DDYDDV

11.42

-9.30

8.46

DDDYDD

13.17

-7.56

10.20

YDDVDI

13.34

-6.75

11.01

Q80U87

YPPEMA

17.41

-5.11

12.65

FRYYHS

17.98

2.56

20.32

Q9Z1S8

ENYVPM

14.47

-8.88

8.88

DNYVPM

14.97

-7.14

10.62

SEENYV

15.51

7.23

24.99

O35601

DDEIYD

12.86

-1.95

15.81

EIYDGI

13.59

-5.63

12.13

DEIYDG

15.42

-5.58

12.18

Q9QYY0

LYTFNT

12.98

-6.16

11.60

DGELYT

13.10

2.33

20.09

PPYQVI

13.82

-6.93

10.83

 


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