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Matrix information:
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ADAN-name: 1QCF2.PDB
Scoring matrix: 1QCF2_mat
Uniprot code: P08631
Genome source: Homo sapiens
Wild-type ligand: ESQyEEIP
Foldx wt ligand score: 7.71
Foldx random average score for Homo sapiens: 17.643 Available information for P08631 in MINT (Nov 2008):
Nš of interacting proteins: 16
Proteins belonging to other specie: 7
Nš of interactions described: 37
Interactions with other species: 17
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22200620
Proteins after random average filtering: 48046
Total fragments: 11945863
Proteins after disorder filtering: 36293
Total fragments: 1237263
Proteins after pattern filtering: 18524
Total fragments: 122635
Proteins after MINT filtering: 5
Total fragments: 33
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
ESQyEEIP |
7.71
|
-12.62 |
0.00 |
| Best peptides |
pssyEsMG |
0.00
|
-10.50 |
2.12 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q13444 |
YCEEGWAP |
12.58
|
-1.71 |
10.91 |
|
HCYCEEGW |
15.67
|
-2.43 |
10.19 |
|
SGSYVSCT |
15.96
|
-3.87 |
8.75 |
| O43516 |
PPPEPYVQ |
14.22
|
-5.41 |
7.21 |
|
PEPYVQTT |
16.23
|
-2.82 |
9.80 |
| Q53H12 |
SYTGPTER |
16.85
|
-2.58 |
10.04 |
| P21860 |
GGDYAAMG |
10.56
|
-4.28 |
8.34 |
|
DEDYEYMN |
11.31
|
-6.91 |
5.71 |
|
SSGYMPMN |
12.15
|
-5.51 |
7.11 |
| P42768 |
SSRYRGLP |
14.75
|
-4.30 |
8.32 |
|
YRGLPAPG |
14.86
|
-1.67 |
10.95 |
|
ITSSRYRG |
16.30
|
-2.08 |
10.54 |
|
