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Matrix information:
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ADAN-name: 1OV32.PDB
Scoring matrix: 1OV32_mat
Uniprot code: P14598
Genome source: Homo sapiens
Wild-type ligand: QPPSNPPPRPP
Foldx wt ligand score: 4.15
Foldx random average score for Homo sapiens: 11.809 Available information for P14598 in MINT (Nov 2008):
Nš of interacting proteins: 11
Proteins belonging to other specie: 2
Nš of interactions described: 21
Interactions with other species: 3
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22056464
Proteins after random average filtering: 48033
Total fragments: 9568768
Proteins after disorder filtering: 33761
Total fragments: 673967
Proteins after pattern filtering: 24718
Total fragments: 284299
Proteins after MINT filtering: 5
Total fragments: 73
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
QPPSNPPPRPP |
4.15
|
-11.07 |
0.00 |
| Best peptides |
FWDEMIVRRRR |
0.00
|
-13.42 |
-2.35 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P19878 |
PQAAEPPPRPK |
4.05
|
-12.49 |
-1.42 |
|
PPSSKAPGRPQ |
5.39
|
-10.61 |
0.46 |
|
AAEPPPRPKTP |
9.77
|
-6.84 |
4.23 |
| Q9C026 |
SPALAPVPRNS |
4.63
|
-10.82 |
0.25 |
|
CRLRCHPPRGP |
5.80
|
-11.09 |
-0.02 |
|
GVRVFPPAMPP |
8.46
|
-7.53 |
3.54 |
| Q04206 |
PTDPRPPPRRI |
3.18
|
-13.26 |
-2.19 |
|
LVTKDPPHRPH |
3.44
|
-12.37 |
-1.30 |
|
TDPRPPPRRIA |
4.12
|
-12.17 |
-1.10 |
| P17252 |
LIPMDPNGLSD |
10.45
|
-5.05 |
6.02 |
| P13498 |
QPPSNPPPRPP |
4.15
|
-12.35 |
-1.28 |
|
GTIKQPPSNPP |
9.43
|
-6.16 |
4.91 |
|
GPPGGPQVNPI |
9.77
|
-5.16 |
5.91 |
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