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Matrix information:
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ADAN-name: 1OPK2.PDB
Scoring matrix: 1OPK2_mat
Uniprot code: P00520
Genome source: Mus musculus
Wild-type ligand: KPTIYGVSP
Foldx wt ligand score: 1.65
Foldx random average score for Mus musculus: 12.137 Available information for P00520 in MINT (Nov 2008):
Nš of interacting proteins: 12
Proteins belonging to other specie: 5
Nš of interactions described: 23
Interactions with other species: 7
Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
Total fragments: 20420010
Proteins after random average filtering: 44443
Total fragments: 10538320
Proteins after disorder filtering: 32840
Total fragments: 1139599
Proteins after pattern filtering: 23067
Total fragments: 255204
Proteins after MINT filtering: 7
Total fragments: 156
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
KPTIYGVSP |
1.65
|
-10.77 |
0.00 |
| Best peptides |
RPRMKGPNP |
0.00
|
-10.73 |
0.04 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q06649 |
PPPVPANKP |
6.23
|
-9.69 |
1.08 |
|
VLPRPENTP |
6.25
|
-7.17 |
3.60 |
|
VPRKPAFSD |
6.91
|
-7.54 |
3.23 |
| Q8CBW3 |
PPPMPQLTP |
3.79
|
-10.17 |
0.60 |
|
GIPIAVPTP |
6.28
|
-8.38 |
2.39 |
|
GPAAPGAAP |
6.31
|
-7.09 |
3.68 |
| O70469 |
RPESPYSRP |
5.40
|
-9.78 |
0.99 |
|
HDSLPSPSP |
5.43
|
-8.96 |
1.81 |
|
PPSLPATGP |
5.99
|
-9.02 |
1.75 |
| O35716 |
CPAVPAPAP |
5.77
|
-9.09 |
1.68 |
|
APVRPRPCP |
6.47
|
-8.82 |
1.95 |
|
RPCPAVPAP |
7.00
|
-8.39 |
2.38 |
| P70429 |
PPPPTGSTP |
5.30
|
-8.25 |
2.52 |
|
EDPSTSPSP |
7.47
|
-4.61 |
6.16 |
|
QTEDPSTSP |
7.69
|
-6.03 |
4.74 |
| P97814 |
LHGSPKTTP |
6.18
|
-6.52 |
4.25 |
|
LIGSPSIQP |
6.72
|
-9.29 |
1.48 |
|
GREPPAPVP |
9.28
|
-5.98 |
4.79 |
| P55194 |
RPTMPPPQP |
6.25
|
-13.69 |
-2.92 |
|
TVPAPATTP |
6.48
|
-6.01 |
4.76 |
|
RPAPARPTM |
7.65
|
-7.72 |
3.05 |
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