ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1OEB2.PDB
Scoring matrix: 1OEB2_mat
Uniprot code: O89100
Genome source: Mus musculus
Wild-type ligand: APSIDRSTKPPL
Foldx wt ligand score: 5.84
Foldx random average score for Mus musculus: 19.643

Available information for O89100 in MINT (Nov 2008):
Nš of interacting proteins: 14
 Proteins belonging to other specie: 8
Nš of interactions described: 28
 Interactions with other species: 14

Genome scanning information:
Subcellular location: False
Proteins in genome Mus musculus: 58346
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 13900
Total scanned proteins: 44446
 Total fragments: 20286681
Proteins after random average filtering: 44437
 Total fragments: 8921342
Proteins after disorder filtering: 29519
 Total fragments: 487836
Proteins after pattern filtering: 20277
 Total fragments: 159684
Proteins after MINT filtering: 6
 Total fragments: 149


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

APSIDRSTKPPL

5.84

-20.02

0.00

Best peptides

RPRRHRHMRMRL

0.00

-19.02

1.00

         
Interactors      
Q9QUN3

PSPLPRAGKKPA

12.14

-16.83

3.19

PFSKTLPSKPSW

13.53

-11.73

8.29

PAAPSPLPRAGK

14.84

-10.60

9.42

P70218

SGPPPRTPRPGP

11.18

-14.67

5.35

RCASGPPPRTPR

14.94

-11.13

8.89

PPPLPPKPKFRS

15.21

-11.25

8.77

Q80U87

PPSTPPTHKVKP

15.25

-11.79

8.23

VPSKLPTQMPPP

16.13

-11.01

9.01

PPEMAPSSAPPS

16.78

-8.96

11.06

Q9Z1S8

DSAIAPPPRPPK

13.09

-14.58

5.44

IAPPPRPPKPSQ

13.32

-14.12

5.90

LSSASHGPRSSP

14.89

-12.18

7.84

O35601

PSLPPRNIKPPL

10.34

-14.33

5.69

TDSKPRFPRHTF

11.05

-14.19

5.83

PPKPNRPPNVDL

12.53

-14.94

5.08

Q9QYY0

DIPPPRPPKPHP

11.77

-16.69

3.33

RPPKPHPTHDRS

13.55

-15.11

4.91

SSPKTPPRRPVP

14.89

-12.16

7.86

 


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