ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1OBZ2.PDB
Scoring matrix: 1OBZ2_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: DSVF
Foldx wt ligand score: 4.69
Foldx random average score for Homo sapiens: 5.327

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22392853
Proteins after random average filtering: 48056
 Total fragments: 11525857
Proteins after disorder filtering: 38211
 Total fragments: 841227
Proteins after pattern filtering: 27930
 Total fragments: 119342
Proteins after MINT filtering: 1
 Total fragments: 3


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

DSVF

4.69

-6.90

0.00

Best peptides

LGLM

0.00

-8.42

-1.52

         
Interactors      
P30203

KSKL

2.61

-7.31

-0.41

ASQL

3.38

-6.03

0.87

PVRL

5.29

-5.35

1.55

 


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