ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1OBY2.PDB
Scoring matrix: 1OBY2_mat
Uniprot code: O00560
Genome source: Homo sapiens
Wild-type ligand: NEFYA
Foldx wt ligand score: 4.46
Foldx random average score for Homo sapiens: 9.303

Available information for O00560 in MINT (Nov 2008):
Nš of interacting proteins: 2
 Proteins belonging to other specie: 0
Nš of interactions described: 3
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
 Total fragments: 22344792
Proteins after random average filtering: 48056
 Total fragments: 13162197
Proteins after disorder filtering: 37825
 Total fragments: 1020664
Proteins after pattern filtering: 28164
 Total fragments: 131887
Proteins after MINT filtering: 1
 Total fragments: 3


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

NEFYA

4.46

-12.47

0.00

Best peptides

FMFMM

0.00

-14.66

-2.19

         
Interactors      
P30203

TTIPA

6.54

-9.21

3.26

PAFSA

7.30

-8.75

3.72

PKSKL

8.44

-9.18

3.29

 


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