ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1N7F2.PDB
Scoring matrix: 1N7F2_mat
Uniprot code: P97879
Genome source: Rattus norvegicus
Wild-type ligand: ATVRTYSC
Foldx wt ligand score: 7.45
Foldx random average score for Rattus norvegicus: 10.581

Available information for P97879 in MINT (Nov 2008):
Nš of interacting proteins: 24
 Proteins belonging to other specie: 6
Nš of interactions described: 65
 Interactions with other species: 12

Genome scanning information:
Subcellular location: False
Proteins in genome Rattus norvegicus: 15006
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 3052
Total scanned proteins: 11954
 Total fragments: 5568889
Proteins after random average filtering: 11951
 Total fragments: 2774125
Proteins after disorder filtering: 8103
 Total fragments: 82526
Proteins after pattern filtering: 4815
 Total fragments: 12063
Proteins after MINT filtering: 13
 Total fragments: 35


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

ATVRTYSC

7.45

-10.20

0.00

Best peptides

KRWMMYMF

0.00

-16.90

-6.70

         
Interactors      
Q9JHZ4

GDVLPISL

9.11

-10.06

0.14

PPGDVLPI

10.27

-8.33

1.87

P54256

VTHYGYSV

8.19

-9.19

1.01

RQRSSMPA

8.53

-10.31

-0.11

HYGYSVPL

8.66

-9.97

0.23

P35400

NGEAKTEL

9.85

-9.06

1.14

P31422

GQWPTADL

9.79

-7.14

3.06

P31423

PHMNSIRI

8.00

-12.04

-1.84

TLGGLFPV

8.26

-10.04

0.16

RIDGDITL

8.75

-8.16

2.04

Q91Z79

LATDPLGL

8.81

-7.61

2.59

APLDPYGA

9.14

-8.27

1.93

DPLGLAKL

9.63

-8.11

2.09

Q9WUL3

MPQGSYMV

5.83

-13.17

-2.97

GKKARLQL

8.13

-11.26

-1.06

PQGSYMVV

9.35

-9.41

0.79

P19493

LDSKGYGV

8.43

-8.60

1.60

QPPNEFGI

8.72

-9.80

0.40

P19492

LDSKGYGV

8.43

-8.60

1.60

DPPNEFGI

9.93

-8.33

1.87

P19491

LDSKGYGI

8.62

-8.68

1.52

P19490

LDSKGYGI

8.62

-8.68

1.52

SHSSGMPL

8.74

-8.73

1.47

Q9QXY2

GDGYGFRL

8.06

-10.69

-0.49

SGSSSVFA

9.62

-7.77

2.43

QKLADVSA

9.64

-7.25

2.95

Q3MUI2

LQPFSAPV

9.10

-8.39

1.81

PTLQPFSA

9.83

-8.64

1.56

VPPMPTMA

10.10

-7.57

2.63

 


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