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Matrix information:
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ADAN-name: 1MFL2.PDB
Scoring matrix: 1MFL2_mat
Uniprot code: Q96RT1
Genome source: Homo sapiens
Wild-type ligand: LDVPV
Foldx wt ligand score: 3.52
Foldx random average score for Homo sapiens: 8.336 Available information for Q96RT1 in MINT (Nov 2008):
Nš of interacting proteins: 7
Proteins belonging to other specie: 1
Nš of interactions described: 17
Interactions with other species: 1
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22344792
Proteins after random average filtering: 48053
Total fragments: 12144480
Proteins after disorder filtering: 37689
Total fragments: 926957
Proteins after pattern filtering: 29126
Total fragments: 150951
Proteins after MINT filtering: 5
Total fragments: 58
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
LDVPV |
3.52
|
-10.06 |
0.00 |
| Best peptides |
DDFYL |
0.00
|
-11.75 |
-1.69 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q9UQB3 |
SAFHL |
3.38
|
-10.26 |
-0.20 |
|
SPVRV |
4.07
|
-9.88 |
0.18 |
|
DSVPL |
4.45
|
-8.79 |
1.27 |
| O95405 |
PTVMV |
2.89
|
-10.50 |
-0.44 |
|
VMVPV |
3.99
|
-10.12 |
-0.06 |
|
GVSFV |
4.06
|
-9.50 |
0.56 |
| O00192 |
SRAYL |
3.21
|
-10.39 |
-0.33 |
|
DDSTL |
3.88
|
-9.82 |
0.24 |
|
GCFTL |
4.13
|
-9.42 |
0.64 |
| P35222 |
ADYPV |
3.73
|
-9.50 |
0.56 |
| Q99569 |
PDSWV |
2.47
|
-10.07 |
-0.01 |
|
SPALL |
3.83
|
-9.82 |
0.24 |
|
SPIYI |
4.12
|
-10.49 |
-0.43 |
|
