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Matrix information:
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ADAN-name: 1MFG2.PDB
Scoring matrix: 1MFG2_mat
Uniprot code: Q96RT1
Genome source: Homo sapiens
Wild-type ligand: EYLGLDVPV
Foldx wt ligand score: 5.1
Foldx random average score for Homo sapiens: 13.669 Available information for Q96RT1 in MINT (Nov 2008):
Nš of interacting proteins: 7
Proteins belonging to other specie: 1
Nš of interactions described: 17
Interactions with other species: 1
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22152566
Proteins after random average filtering: 48047
Total fragments: 12210698
Proteins after disorder filtering: 35857
Total fragments: 945814
Proteins after pattern filtering: 26351
Total fragments: 125202
Proteins after MINT filtering: 5
Total fragments: 51
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
EYLGLDVPV |
5.10
|
-11.49 |
0.00 |
| Best peptides |
WYDGDHILV |
0.00
|
-12.43 |
-0.94 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| Q9UQB3 |
PSLGSAFHL |
9.24
|
-9.68 |
1.81 |
|
PQGGSPTKL |
9.40
|
-9.33 |
2.16 |
|
SPGVDSVPL |
10.05
|
-10.02 |
1.47 |
| O95405 |
SPVGSAMNL |
8.15
|
-8.14 |
3.35 |
|
DSGGQCVGL |
8.83
|
-7.21 |
4.28 |
|
PKQPSNLKL |
8.87
|
-10.28 |
1.21 |
| O00192 |
GFDDSTLPL |
6.15
|
-10.56 |
0.93 |
|
GPGDGCFTL |
8.15
|
-8.94 |
2.55 |
|
PGHREAFPV |
8.94
|
-9.47 |
2.02 |
| P35222 |
HHPGADYPV |
8.54
|
-9.54 |
1.95 |
|
IHSGATTTA |
13.21
|
-2.98 |
8.51 |
| Q99569 |
SFPWRSTDV |
8.07
|
-10.69 |
0.80 |
|
STSSSPALL |
9.47
|
-8.21 |
3.28 |
|
PKRSGMTAV |
9.68
|
-8.62 |
2.87 |
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