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Matrix information:
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ADAN-name: 1LKL2.PDB
Scoring matrix: 1LKL2_mat
Uniprot code: P06239
Genome source: Homo sapiens
Wild-type ligand: yEEG
Foldx wt ligand score: 1.03
Foldx random average score for Homo sapiens: 14.155 Available information for P06239 in MINT (Nov 2008):
Nš of interacting proteins: 20
Proteins belonging to other specie: 3
Nš of interactions described: 50
Interactions with other species: 22
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22392853
Proteins after random average filtering: 48059
Total fragments: 16831006
Proteins after disorder filtering: 38924
Total fragments: 2608581
Proteins after pattern filtering: 20355
Total fragments: 130507
Proteins after MINT filtering: 12
Total fragments: 69
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
yEEG |
1.03
|
-7.05 |
0.00 |
| Best peptides |
yDyA |
0.00
|
-7.61 |
-0.56 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P20963 |
LYQG |
9.15
|
-0.74 |
6.31 |
|
GLYQ |
12.70
|
-0.24 |
6.81 |
| P04150 |
GYSS |
11.60
|
0.53 |
7.58 |
|
NGYS |
12.20
|
1.44 |
8.49 |
|
YSSP |
13.65
|
0.86 |
7.91 |
| P28482 |
GYRS |
11.94
|
0.79 |
7.84 |
| P22681 |
YDDD |
9.84
|
1.20 |
8.25 |
|
TEYM |
9.89
|
-1.33 |
5.72 |
|
PYSV |
10.56
|
-0.53 |
6.52 |
| Q07666 |
YDYG |
7.96
|
-1.38 |
5.67 |
|
EYYD |
11.24
|
-0.04 |
7.01 |
|
YSQS |
11.73
|
0.97 |
8.02 |
| Q13283 |
YVHG |
9.32
|
-0.21 |
6.84 |
|
SSYV |
11.74
|
0.22 |
7.27 |
| P27986 |
YNET |
12.17
|
1.75 |
8.80 |
|
GYNE |
13.20
|
-1.56 |
5.49 |
| Q13094 |
DYES |
9.72
|
-0.29 |
6.76 |
|
DDYE |
10.02
|
-3.72 |
3.33 |
|
PYFS |
10.80
|
0.24 |
7.29 |
| Q13444 |
YVSC |
9.11
|
-0.99 |
6.06 |
|
HCYC |
10.69
|
0.38 |
7.43 |
|
GSYV |
11.71
|
0.57 |
7.62 |
| Q12959 |
DGYA |
9.33
|
-1.83 |
5.22 |
|
PTYV |
11.04
|
0.15 |
7.20 |
|
ARYS |
11.15
|
0.44 |
7.49 |
| P43405 |
YDVV |
9.00
|
-2.09 |
4.96 |
|
YSFP |
13.43
|
0.55 |
7.60 |
| P43403 |
VYES |
10.06
|
-0.31 |
6.74 |
|
EFYS |
10.43
|
-0.47 |
6.58 |
|
YESP |
11.36
|
-2.89 |
4.16 |
|
