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Matrix information:
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ADAN-name: 1LKK2.PDB
Scoring matrix: 1LKK2_mat
Uniprot code: P06239
Genome source: Homo sapiens
Wild-type ligand: yEEI
Foldx wt ligand score: 1.6
Foldx random average score for Homo sapiens: 13.043 Available information for P06239 in MINT (Nov 2008):
Nš of interacting proteins: 20
Proteins belonging to other specie: 3
Nš of interactions described: 50
Interactions with other species: 22
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 22392853
Proteins after random average filtering: 48057
Total fragments: 11959802
Proteins after disorder filtering: 37907
Total fragments: 1451006
Proteins after pattern filtering: 17092
Total fragments: 58245
Proteins after MINT filtering: 9
Total fragments: 38
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
yEEI |
1.60
|
-12.43 |
0.00 |
| Best peptides |
yEsM |
0.00
|
-12.29 |
0.14 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P04150 |
YSSP |
12.57
|
-3.71 |
8.72 |
| P27986 |
YNET |
11.30
|
-4.40 |
8.03 |
|
GYNE |
12.56
|
-4.04 |
8.39 |
| P22681 |
TEYM |
10.10
|
-5.01 |
7.42 |
|
YDDD |
10.61
|
-5.37 |
7.06 |
|
YDVP |
11.12
|
-4.94 |
7.49 |
| Q07666 |
TYEE |
11.03
|
-3.62 |
8.81 |
|
ETYE |
12.30
|
-5.39 |
7.04 |
| Q13444 |
YCEE |
11.23
|
-4.61 |
7.82 |
|
YVSC |
12.06
|
-3.88 |
8.55 |
|
CYCE |
12.46
|
-3.40 |
9.03 |
| Q13094 |
DYEP |
10.08
|
-5.46 |
6.97 |
|
YESP |
10.22
|
-6.30 |
6.13 |
|
YEPP |
10.44
|
-5.21 |
7.22 |
| Q12959 |
YAPP |
12.01
|
-4.78 |
7.65 |
|
GYAP |
12.47
|
-3.27 |
9.16 |
|
MYMN |
12.47
|
-2.80 |
9.63 |
| P43405 |
YDVV |
12.26
|
-3.00 |
9.43 |
| P43403 |
YESP |
10.22
|
-6.30 |
6.13 |
|
SVYE |
12.29
|
-2.55 |
9.88 |
|
GYTP |
12.32
|
-3.40 |
9.03 |
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