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Matrix information:
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ADAN-name: 1K4U2.PDB
Scoring matrix: 1K4U2_mat
Uniprot code: P14598
Genome source: Homo sapiens
Wild-type ligand: SKPQPAVPPRPSA
Foldx wt ligand score: 6.27
Foldx random average score for Homo sapiens: 10.672 Available information for P14598 in MINT (Nov 2008):
Nš of interacting proteins: 11
Proteins belonging to other specie: 2
Nš of interactions described: 21
Interactions with other species: 3
Genome scanning information:
Subcellular location: False
Proteins in genome Homo sapiens: 70890
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 22829
Total scanned proteins: 48061
Total fragments: 21960385
Proteins after random average filtering: 48023
Total fragments: 10825085
Proteins after disorder filtering: 33870
Total fragments: 984733
Proteins after pattern filtering: 25097
Total fragments: 454050
Proteins after MINT filtering: 5
Total fragments: 113
Prediction of know targets:
| Ligand peptide |
Sequence |
Foldx score |
ΔGbinding |
ΔΔG |
| Reference wt |
SKPQPAVPPRPSA |
6.27
|
-9.69 |
0.00 |
| Best peptides |
RIRRPRRGRRMRH |
0.00
|
-1.75 |
7.94 |
| |
|
|
|
|
| Interactors |
|
|
|
|
| P19878 |
SSKAPGRPQLSPG |
7.38
|
-6.07 |
3.62 |
|
DIPAPPSSKAPGR |
7.50
|
-7.29 |
2.40 |
|
APLQPQAAEPPPR |
7.52
|
-7.72 |
1.97 |
| Q9C026 |
LRCHPPRGPLAKH |
4.98
|
-11.33 |
-1.64 |
|
NGVRVFPPAMPPP |
6.05
|
-8.79 |
0.90 |
|
CRLRCHPPRGPLA |
6.24
|
-11.27 |
-1.58 |
| Q04206 |
PPHRPHPHELVGK |
5.20
|
-9.49 |
0.20 |
|
PLRLPPVLSHPIF |
5.80
|
-9.76 |
-0.07 |
|
SVPKPAPQPYPFT |
6.44
|
-9.09 |
0.60 |
| P17252 |
LIPMDPNGLSDPY |
9.55
|
-2.43 |
7.26 |
| P13498 |
GTIKQPPSNPPPR |
7.97
|
-7.39 |
2.30 |
|
KQPPSNPPPRPPA |
7.99
|
-8.05 |
1.64 |
|
TIKQPPSNPPPRP |
8.11
|
-8.19 |
1.50 |
|
