ADAN database

 

Scanning Information and Binding Energy of Known Targets

Matrix information:                                                    (Help)
ADAN-name: 1IHJ2.PDB
Scoring matrix: 1IHJ2_mat
Uniprot code: Q24008
Genome source: Drosophila melanogaster
Wild-type ligand: TEFCA
Foldx wt ligand score: 1.45
Foldx random average score for Drosophila melanogaster: 9.221

Available information for Q24008 in MINT (Nov 2008):
Nš of interacting proteins: 10
 Proteins belonging to other specie: 0
Nš of interactions described: 11
 Interactions with other species: 0

Genome scanning information:
Subcellular location: False
Proteins in genome Drosophila melanogaster: 30509
Proteins located in other compartments: 0
Proteins considered as fragments or having non-standard amino acids: 4389
Total scanned proteins: 26120
 Total fragments: 13435359
Proteins after random average filtering: 26120
 Total fragments: 8430626
Proteins after disorder filtering: 20927
 Total fragments: 956242
Proteins after pattern filtering: 14880
 Total fragments: 82735
Proteins after MINT filtering: 8
 Total fragments: 54


Prediction of know targets:

Ligand peptide Sequence Foldx score ΔGbinding ΔΔG
Reference wt

TEFCA

1.45

-8.80

0.00

Best peptides

MPFCN

0.00

-10.22

-1.42

         
Interactors      
Q9VY31

IQYGA

4.85

-6.26

2.54

PQFAA

5.59

-5.81

2.99

QIFDA

5.72

-6.00

2.80

Q9VVK7

QGYYA

6.08

-5.37

3.43

GYYAA

6.84

-5.98

2.82

TFFSI

8.46

-6.89

1.91

Q9VBP2

NNYAV

6.44

-7.05

1.75

MGAPA

6.93

-6.64

2.16

NGALV

7.74

-7.58

1.22

Q9V3H0

VDSLA

8.44

-5.51

3.29

Q9VK43

DGMEL

5.86

-8.12

0.68

SPSGA

8.21

-3.04

5.76

TPTSA

9.21

-3.44

5.36

P13217

CGYLL

5.28

-7.77

1.03

EAAAA

7.13

-4.04

4.76

PGLPL

7.52

-7.37

1.43

Q9XTL2

ALYGA

5.99

-4.68

4.12

PGYPA

6.75

-6.53

2.27

PGAAL

7.73

-6.21

2.59

Q8T0N2

GELEV

7.41

-6.02

2.78

KCSSV

9.08

-4.61

4.19

KNSPV

9.13

-5.68

3.12

 


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